Tryptophan 5-monooxygenase

Known as: Tryptophan Monooxygenase, Monooxygenase, Tryptophan, Hydroxylase, Tryptophan 
An enzyme that catalyzes the hydroxylation of TRYPTOPHAN to 5-HYDROXYTRYPTOPHAN in the presence of NADPH and molecular oxygen. It is important in the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1952-2017
05010015019522016

Papers overview

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Highly Cited
2008
Highly Cited
2008
Half a century ago, chronic granulomatous disease (CGD) was first described as a disease fatally affecting the ability of… (More)
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Highly Cited
2006
Highly Cited
2006
The liver can regenerate its volume after major tissue loss. In a mouse model of liver regeneration, thrombocytopenia, or… (More)
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Highly Cited
2004
Highly Cited
2004
We report analyses from a study of gene–environment interaction in adolescent depression. The sample was selected from 1990… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND & AIMS Serotonin (5-HT) is a critical signaling molecule in the gut. 5-HT released from enterochromaffin cells… (More)
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Highly Cited
2003
Highly Cited
2003
Highly Cited
2003
Serotonin (5-hydroxytryptophan, 5-HT) is a neurotransmitter synthesized in the raphe nuclei of the brain stem and involved in the… (More)
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Highly Cited
2000
Highly Cited
2000
The functions of serotonin have been assigned through serotonin-receptor-specific drugs and mutants; however, because a… (More)
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Highly Cited
1992
Highly Cited
1992
Neurological dysfunction, seizures and brain atrophy occur in a broad spectrum of acute and chronic neurological diseases. In… (More)
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Highly Cited
1990
Highly Cited
1990
Two anthranilate synthase gene pairs have been identified in Pseudomonas aeruginosa. They were cloned, sequenced, inactivated in… (More)
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Highly Cited
1983
Highly Cited
1983
A current hypothesis links the neuroexcitatory properties of certain acidic amino acids to their ability to cause selective… (More)
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