TPH2 gene

Known as: NTPH, TPH2, TRYPTOPHAN HYDROXYLASE 2 
 
National Institutes of Health

Papers overview

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2012
2012
Probably the foremost hypothesis of depression is the 5-hydroxytryptamine (5-HT, serotonin) deficiency hypothesis. Accordingly… (More)
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2011
2011
In the brain, serotonin production is controlled by tryptophan hydroxylase 2 (TPH2), a genotype. Previous studies found that… (More)
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Highly Cited
2008
Highly Cited
2008
Dysregulation of brain serotonin (5-HT) neurotransmission is thought to underlie mental conditions as diverse as depression… (More)
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2007
2007
The neurotransmitter serotonin [5-hydroxytryptamine (5-HT)] controls a broad range of biological functions that are disturbed in… (More)
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2007
2007
Current models of attention describe attention not as a homogenous entity but as a set of neural networks whose measurement… (More)
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2007
2007
Tryptophan Hydroxylase 2 (TPH2) is the rate-limiting enzyme in the biosynthesis of serotonin which is exclusively expressed in… (More)
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Highly Cited
2007
Highly Cited
2007
CONTEXT The tryptophan hydroxylase 2 (TPH2) gene encodes the first (also the rate-limiting) enzyme in the serotonin biosynthetic… (More)
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2006
2006
CONTEXT Tryptophan hydroxylase is the rate-limiting enzyme in the serotonin (5-HT) biosynthetic pathway responsible for the… (More)
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Highly Cited
2005
Highly Cited
2005
Genetic and pharmacological studies have emphasised the role of serotonin 5-hydroxytryptamine (5-HT) as a possible etiologic… (More)
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Highly Cited
2002
Highly Cited
2002
Tryptophan hydroxylase isoform 2 (TPH2) is expressed in serotonergic neurons in the raphe nuclei, where it catalyzes the rate… (More)
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