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TPH2 gene

Known as: NTPH, TPH2, TRYPTOPHAN HYDROXYLASE 2 
National Institutes of Health

Related topics

Related topics

3 relations
TPH1 geneTPH1 protein, humanTryptophan 5-monooxygenase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Life without brain serotonin: Reevaluation of serotonin function with mice deficient in brain serotonin synthesis
Highly Cited
2014
Highly Cited
2014
Neurochemical Effects of Chronic Administration of Calcitriol in Rats
Despite accumulating data showing the various neurological actions of vitamin D (VD), its effects on brain neurochemistry are… 
Highly Cited
2012
Highly Cited
2012
Exaggerated aggression and decreased anxiety in mice deficient in brain serotonin
Serotonin is a major neurotransmitter in the central nervous system (CNS). Dysregulation of serotonin transmission in the CNS is… 
Highly Cited
2011
Highly Cited
2011
Molecular regulation of sexual preference revealed by genetic studies of 5-HT in the brains of male mice
Although the question of to whom a male directs his mating attempts is a critical one in social interactions, little is known… 
Highly Cited
2009
Highly Cited
2009
Adverse experience during early life and adulthood interact to elevate tph2 mRNA expression in serotonergic neurons within the dorsal raphe nucleus
Highly Cited
2009
Highly Cited
2009
Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain
Monoaminergic neurons include the physiologically important central serotonergic and noradrenergic subtypes. Here, we identify… 
Highly Cited
2007
Highly Cited
2007
Characterization of a Functional Promoter Polymorphism of the Human Tryptophan Hydroxylase 2 Gene in Serotonergic Raphe Neurons
Highly Cited
2007
Highly Cited
2007
Tryptophan hydroxylase 2 (TPH2) haplotypes predict levels of TPH2 mRNA expression in human pons
Tryptophan hydroxylase isoform 2 (TPH2) is expressed in serotonergic neurons in the raphe nuclei, where it catalyzes the rate… 
Highly Cited
2005
Highly Cited
2005
Tryptophan hydroxylase 2 (TPH2) gene variants associated with ADHD
Genetic and pharmacological studies have emphasised the role of serotonin 5-hydroxytryptamine (5-HT) as a possible etiologic… 
Highly Cited
1994
Highly Cited
1994
Sequencing and characterization of the ntp gene cluster for vacuolar-type Na(+)-translocating ATPase of Enterococcus hirae.
We have previously reported the DNA and amino acid sequences for the three genes (ntpA, ntpB, and ntpK) encoding the A, B, and K… 
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