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Structure of the Rotor of the V-Type Na+-ATPase from Enterococcus hirae
The membrane rotor ring from the vacuolar-type (V-type) sodium ion–pumping adenosine triphosphatase (Na+-ATPase) from Enterococcus hirae consists of 10 NtpK subunits, which are homologs of theExpand
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Rotation mechanism of Enterococcus hirae V1-ATPase based on asymmetric crystal structures
In various cellular membrane systems, vacuolar ATPases (V-ATPases) function as proton pumps, which are involved in many processes such as bone resorption and cancer metastasis, and these membraneExpand
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Multiple polyamine transport systems on the vacuolar membrane in yeast.
We recently identified a gene (TPO1, YLL028w) that encodes a polyamine transport protein on the vacuolar membrane in yeast [Tomitori, Kashiwagi, Sakata, Kakinuma and Igarashi (1999) J. Biol. Chem.Expand
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Identification of a Gene for a Polyamine Transport Protein in Yeast*
Properties of a membrane protein encoded byYLL028w were examined using yeast cells transformed with the gene. The transformed cells became resistant to polyamine toxicity, and the resistance wasExpand
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Inorganic Cation Transport and Energy Transduction in Enterococcus hirae and Other Streptococci
  • Y. Kakinuma
  • Medicine, Biology
  • Microbiology and Molecular Biology Reviews
  • 1 December 1998
SUMMARY Energy metabolism by bacteria is well understood from the chemiosmotic viewpoint. We know that bacteria extrude protons across the plasma membrane, establishing an electrochemical potentialExpand
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A Family of Basic Amino Acid Transporters of the Vacuolar Membrane from Saccharomyces cerevisiae*
Among the members of the major facilitator superfamily of Saccharomyces cerevisiae, we identified genes involved in the transport into vacuoles of the basic amino acids histidine, lysine, andExpand
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Properties of H+-translocating adenosine triphosphatase in vacuolar membranes of SAccharomyces cerevisiae.
The properties of Mg2+-ATPase in the vacuole of Saccharomyces cerevisiae were studied, using purified intact vacuoles and right-side-out vacuolar membrane vesicles prepared by the method of Y. OhsumiExpand
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Renin-dependent Cardiovascular Functions and Renin-independent Blood-Brain Barrier Functions Revealed by Renin-deficient Mice*
Renin plays a key role in controlling blood pressure through its specific cleavage of angiotensinogen to generate angiotensin I (AI). Although possible existence of the other angiotensin formingExpand
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Proton gradient-driven nickel uptake by vacuolar membrane vesicles of Saccharomyces cerevisiae.
A vacuolar H+-ATPase-negative mutant of Saccharomyces cerevisiae was highly sensitive to nickel ion. Accumulation of nickel ion in the cells of this mutant of less than 60% of the value for theExpand
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Catalytic properties of Na(+)-translocating V-ATPase in Enterococcus hirae.
V-ATPases make up a family of proton pumps distributed widely from bacteria to higher organisms. We found a variant of this family, a Na(+)-translocating ATPase, in a Gram-positive bacterium,Expand
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