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- Publications
- Influence
Brain-gut axis and its role in the control of food intake.
- S. Konturek, J. Konturek, T. Pawlik, Tomasz M. Brzozowski
- Biology, Medicine
- Journal of physiology and pharmacology : an…
- 1 March 2004
Gastrointestinal tract (GIT) and nervous system, both central (CNS) and enteric (ENS), are involved in two-way extrinsic communication by parasympathetic and sympathetic nerves, each comprising… Expand
Stress and the gut: pathophysiology, clinical consequences, diagnostic approach and treatment options.
- P. Konturek, T. Brzozowski, S. Konturek
- Medicine
- Journal of physiology and pharmacology : an…
- 1 December 2011
Stress, which is defined as an acute threat to homeostasis, shows both short- and long-term effects on the functions of the gastrointestinal tract. Exposure to stress results in alterations of the… Expand
Effects of reactive oxygen species action on gastric mucosa in various models of mucosal injury.
- S. Kwiecien, Tomasz M. Brzozowski, S. Konturek
- Chemistry, Medicine
- Journal of physiology and pharmacology : an…
- 1 March 2002
BACKGROUND
The exposure of gastric mucosa to damaging factors, such as ethanol, water restraint stress, or ischemia followed by reperfusion, produces pathological changes: inflammatory process,… Expand
Neuro-hormonal control of food intake: basic mechanisms and clinical implications.
- P. Konturek, J. Konturek, M. Cześnikiewicz-Guzik, T. Brzozowski, E. Sito, S. Konturek
- Medicine, Biology
- Journal of physiology and pharmacology : an…
- 1 December 2005
Obesity is one of the most common metabolic diseases and the greatest threats of the health because of possibility of numerous complications. In order to design effective drugs or apply the helpful… Expand
Basal and postprandial plasma levels of PYY, ghrelin, cholecystokinin, gastrin and insulin in women with moderate and morbid obesity and metabolic syndrome.
- K. Żwirska-Korczala, S. Konturek, +9 authors Tomasz M. Brzozowski
- Medicine
- Journal of physiology and pharmacology : an…
- 1 March 2007
Metabolic syndrome (MS), defined as central obesity, hyperinsulinemia, insulin resistance, hypertension, dyslipidemia and glucose intolerance, has been associated with inflammatory biomarkers and… Expand
Localization and biological activities of melatonin in intact and diseased gastrointestinal tract (GIT).
- S. Konturek, P. Konturek, +7 authors W. Pawlik
- Biology, Medicine
- Journal of physiology and pharmacology : an…
- 1 September 2007
Melatonin (MT), an indole formed enzymatically from L-trytophan (Trp), was first discovered in the bovine pineal gland in 1958 by Lerner et al. Melatonin is the most versatile and ubiquitous hormonal… Expand
Gut clock: implication of circadian rhythms in the gastrointestinal tract.
- P. Konturek, T. Brzozowski, S. Konturek
- Biology, Medicine
- Journal of physiology and pharmacology : an…
- 1 April 2011
Circadian and seasonal rhythms are a fundamental feature of all living organisms and their organelles. Biological rhythms are responsible for daily food intake; the period of hunger and satiety is… Expand
Role of endogenous nitric oxide in the control of canine pancreatic secretion and blood flow.
- S. Konturek, J. Bilski, P. K. Konturek, M. Cieszkowski, W. Pawlik
- Medicine
- Gastroenterology
- 1 March 1993
BACKGROUND
Endogenous nitric oxide has been implicated in the control of mesenteric circulation, but its role in the control of pancreatic blood flow and exocrine pancreatic secretion has not been… Expand
Classic NSAID and selective cyclooxygenase (COX)‐1 and COX‐2 inhibitors in healing of chronic gastric ulcers
- T. Brzozowski, P. Konturek, +5 authors E. Hahn
- Medicine
- Microscopy research and technique
- 1 June 2001
Prostaglandins (PG) derived from COX‐1 are essential for the maintenance of mucosal integrity but COX‐2 isoform synthesizes PG at a site of inflammation. Recently, COX‐2 mRNA expression was… Expand
Role of prostaglandins in gastroprotection and gastric adaptation.
- T. Brzozowski, P. Konturek, S. Konturek, I. Brzozowska, T. Pawlik
- Medicine
- Journal of physiology and pharmacology : an…
- 1 September 2005
Since Robert discovery that pretreatment with prostaglandin (PG) applied in non-antisecretory dose can prevent the injury of gastric mucosa induced by necrotizing agents, much attention was paid to… Expand