Truncated BID

Known as: Truncated BH3-Interacting Domain Death Agonist, tBID 
Truncated BID is encoded by the human BID gene and is a C-terminal peptide that results from caspase-8 cleavage of the BH3-interacting domain death… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Apoptosis is a form of programmed cell death that is regulated by the Bcl-2 family and caspase family of proteins. The caspase… (More)
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Highly Cited
2009
Highly Cited
2009
Truncated BID (tBID), a proapoptotic BCL2 family protein, induces BAK/BAX-dependent release of cytochrome c and other… (More)
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Highly Cited
2006
Highly Cited
2006
Although the BCL-2 family constitutes a crucial checkpoint in apoptosis, the intricate interplay between these family members… (More)
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Highly Cited
2006
Highly Cited
2006
Engagement of death receptors such as tumor necrosis factor-R1 and Fas brings about the cleavage of cytosolic Bid to truncated… (More)
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Highly Cited
2004
Highly Cited
2004
The serine/threonine kinase Akt/protein kinase B inhibits apoptosis induced by a variety of stimuli, including overexpression or… (More)
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Highly Cited
2004
Highly Cited
2004
Release of cytochrome c from the mitochondrial intermembrane space is critical to apoptosis induced by a variety of death stimuli… (More)
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Highly Cited
2003
Highly Cited
2003
Caspase-8 cleaves BID to tBID, which targets mitochondria and induces oligomerization of BAX and BAK within the outer membrane… (More)
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Highly Cited
2000
Highly Cited
2000
TNFR1/Fas engagement results in the cleavage of cytosolic BID to truncated tBID, which translocates to mitochondria… (More)
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Highly Cited
2000
Highly Cited
2000
The adenovirus E1B 19K gene product is an inhibitor of apoptosis induced by tumor necrosis factor-alpha (TNF-alpha) during viral… (More)
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Highly Cited
1998
Highly Cited
1998
We report here that BID, a BH3 domain-containing proapoptotic Bcl2 family member, is a specific proximal substrate of Casp8 in… (More)
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