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Thromboxane A2 Receptor

Known as: Prostanoid TP Receptor, Receptors, Thromboxane A2, TBXA2R 
Thromboxane A2 receptor (343 aa, ~37 kDa) is encoded by the human TBXA2R gene. This protein is involved in both the stimulation of platelet… 
National Institutes of Health

Related topics

Related topics

14 relations
G Protein-Coupled Receptor GenesG Protein-Coupled Receptor SignalingIntegral Membrane ProteinsLigand Binding

Broader (1)

Receptors, Thromboxane A2, Prostaglandin H2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2005
Review
2005
Angiotensin II and the Endothelium: Diverse Signals and Effects
The initial view of the renin-angiotensin system focused on the role of angiotensin II as a hormone involved in blood pressure… 
Highly Cited
2005
Highly Cited
2005
Coupling interaction between thromboxane A2 receptor and alpha-13 subunit of guanine nucleotide-binding protein.
G protein-coupled receptors (GPCRs) form a large superfamily of membrane proteins that play an essential role in modulating many… 
Highly Cited
2000
Highly Cited
2000
Cardiovascular Responses to the Isoprostanes iPF2α-III and iPE2-III Are Mediated via the Thromboxane A2 Receptor In Vivo
Background—Isoprostanes (iPs) are free radical–catalyzed products of arachidonic acid that reflect lipid peroxidation in vivo… 
Highly Cited
1997
Highly Cited
1997
The Human Thromboxane A2 Receptor α Isoform (TPα) Functionally Couples to the G Proteins Gq and G11 In Vivo and is Activated by the Isoprostane 8-epi Prostaglandin F2α
To establish whether the thromboxane A2 (TXA2) receptor (TP) functionally couples to the Gq family of heterotrimeric G proteins… 
Highly Cited
1996
Highly Cited
1996
Two thromboxane A2 receptor isoforms in human platelets. Opposite coupling to adenylyl cyclase with different sensitivity to Arg60 to Leu mutation.
Thromboxane A2 (TXA2) receptor is a key molecule in hemostasis as its abnormality leads to bleeding disorders. Two isoforms of… 
Highly Cited
1995
Highly Cited
1995
Alternative splicing produces a divergent cytoplasmic tail in the human endothelial thromboxane A2 receptor.
Thromboxane A, (TxAJ causes contraction of vascular smooth muscle and aggregation of platelets; paradoxically, it also induces… 
Highly Cited
1994
Highly Cited
1994
Additions and Corrections to Alternative splicing produces a divergent cytoplasmic tail in the human endothelial thromboxane A2 receptor.
Thromboxane A2 (TxA2) causes contraction of vascular smooth muscle and aggregation of platelets; paradoxically, it also induces… 
Highly Cited
1994
Highly Cited
1994
cDNA cloning of a mouse prostacyclin receptor. Multiple signaling pathways and expression in thymic medulla.
Highly Cited
1993
Highly Cited
1993
Modeling of human thromboxane A2 receptor and analysis of the receptor-ligand interaction.
In order to elucidate the mode of the thromboxane A2 (TXA2) receptor-ligand interaction at the molecular level, a model for the… 
Highly Cited
1990
Highly Cited
1990
Thromboxane A2 Receptor Antagonists Inhibit Endothelium‐Dependent Contractions
Endothelium-dependent contractions to acetylcholine and endothelium-independent contractions to oxygen-derived free radicals in… 
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