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Thermolysin

Known as: Bacillus thermoproteolyticus neutral proteinase, Thermolysin [Chemical/Ingredient] 
A thermostable extracellular metalloendopeptidase containing four calcium ions. (Enzyme Nomenclature, 1992) 3.4.24.27.
National Institutes of Health

Related topics

Related topics

13 relations
In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects

Narrower (2)

Liberasealpha-2-macroglobulin-thermolysin complex

Broader (3)

MetalloendopeptidasesMetalloproteasesmetalloenzyme

Papers overview

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Highly Cited
1986
Highly Cited
1986
Kinetics and equilibrium of enzymatic synthesis of peptides in aqueous/organic biphasic systems. Thermolysin-catalyzed synthesis of N-(benzyloxycarbonyl)-L-aspartyl-L-phenylalanine methyl ester.
We studied kinetics and the equilibrium relationship for the thermolysin-catalyzed synthesis of N-(benzyloxycarbonyl)-L-aspartyl… 
1984
1984
Identification of a thermolysin-like metalloendopeptidase in serum: activity in normal subjects and in patients with sarcoidosis.
A thermolysin-like metalloendopeptidase, optimally active at a neutral pH, was identified in human serum. The enzyme cleaves the… 
1983
1983
Structural analysis of the inhibition of thermolysin by an active-site-directed irreversible inhibitor.
The mode of binding of the irreversible thermolysin inhibitor ClCH2CO-DL-(N-OH)Leu-OCH3 [Rasnick, D., & Powers, J.C. (1978… 
1983
1983
Protease-sensitive regions in myosin subfragment 1.
Proteolytic digestions of myosin subfragment 1 (S-1) with elastase, subtilisin, papain, thermolysin, and Staphylococcus aureus… 
Highly Cited
1980
Highly Cited
1980
Peptide bond synthesis catalyzed by thermolysin.
The coupling between Cbz-Phe-OH and Leu-NH2 catalyzed by thermolysin was examined under various experimental conditions. The… 
Highly Cited
1980
Highly Cited
1980
The complete amino-acid sequence of elongation factor Tu from Escherichia coli.
The complete primary structure of elongation factor Tu from Escherichia coli has been elucidated. The protein, which is a mixture… 
Highly Cited
1978
Highly Cited
1978
Organization of rhodopsin in photoreceptor membranes. 2. Transmembrane organization of bovine rhodopsin: evidence from proteolysis and lactoperoxidase-catalyzed iodination of native and reconstituted…
Proteolysis of reconstituted membranes with papain and thermolysin reveals the existence of two rhodopsin populations: one… 
1975
1975
Evidence of homologous relationship between thermolysin and neutral protease A of Bacillus subtilis.
A comparison of the partial amino-acid sequence of neutral protease A from Bacillus subtilis with the structure of thermolysin… 
Highly Cited
1974
Highly Cited
1974
Covalent structure of calf-thymus ALK-histone.
Highly purified calf thymus ALK-histone (histone rich in alanine, lecine and lysine) was isolated from F2a2 histone fraction by… 
1968
1968
Cytochrome c2 of Rhodospirillum rubrum. 1. Molecular properties of the protein and amino acid sequences of its peptides derived by the action of trypsin and thermolysin.
Abstract The molecular properties of cytochrome c2 isolated from light grown cells of the facultative photoanaerobe…