Metalloproteases

Known as: Metallopeptidase, Metalloproteinases, METALLOPROTEASE 
A proteolytic enzyme that uses a metal ion, usually zinc, to catalyze the hydrolysis of peptide bonds. This protease is inhibited by metal chelating… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Macrophages regulate tissue regeneration following injury. They can worsen tissue injury by producing reactive oxygen species and… (More)
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Review
2017
Review
2017
A compelling long-term goal of cancer biology is to understand the crucial players during tumorigenesis in order to develop new… (More)
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Review
2016
Review
2016
Matrix metalloproteinases are versatile endopeptidases with many different functions in the body in health and disease. In the… (More)
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Highly Cited
2005
Highly Cited
2005
Protease-activated receptors (PARs) are a unique class of G protein-coupled receptors that play critical roles in thrombosis… (More)
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Review
2002
Review
2002
Matrix metalloproteinases (MMPs) have long been associated with cancer-cell invasion and metastasis. This provided the rationale… (More)
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Review
2000
Review
2000
Zinc metalloproteases produced by human pathogenic microorganisms show a wide variety of pathological actions. In local… (More)
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Highly Cited
2000
Highly Cited
2000
The Notch1 receptor is presented at the cell membrane as a heterodimer after constitutive processing by a furin-like convertase… (More)
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Highly Cited
1999
Highly Cited
1999
Amyloid beta peptide (Abeta), the principal proteinaceous component of amyloid plaques in brains of Alzheimer's disease patients… (More)
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Highly Cited
1995
Highly Cited
1995
Matrix metalloproteases are secreted by mammalian cells as zymogens and, upon activation, initiate tissue remodeling by… (More)
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Review
1994
Review
1994
A scheme based on the zinc binding site [1992, FEBS Lett. 312, 110-114] has been extended to classify zinc metalloproteases into… (More)
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