Liberase

OBJECTIVE To set up a protocol to isolate human preantral follicles with an enzyme produced in good manufacturing practice… Expand

For more than a decade Liberase HI was commonly used as the standard enzyme blend for clinical human islet isolation until… Expand

BACKGROUND The purpose of this study is to evaluate the effectiveness of a standardized mixture of purified enzymes (Liberase… Expand

Objective: To determine whether pancreatic islet transplantation can control diabetes and prevent severe life‐threatening… Expand

Background. A two-layer (University of Wisconsin solution/perfluorochemical [UW/PFC]) cold-storage method delivers sufficient… Expand

Background. Primary nonfunction resulting in immediate graft loss is responsible for the failure of a large number of islet… Expand

Introduction Islet transplantation is an attractive solution for type I diabetes, but the results are at the present discouraging… Expand

BACKGROUND Frequent success in human islet isolation is prevented by the large variability of scarce organ donors; this favors… Expand

To determine the effects of procedural modifications, 23 human islet isolations were analyzed. Isolations were divided into two… Expand

Enzymatic digestion of donor pancreases is a vital step in human and large mammalian islet isolation. The variable enzymatic… Expand