Liberase
National Institutes of Health
Papers overview
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The choice of enzyme blend is critical for successful islet isolation. Islet yield, viability, integrity, and function are…
For more than a decade Liberase HI was commonly used as the standard enzyme blend for clinical human islet isolation until…
Islet transplantation has found its niche in diabetes treatment. It has contributed to a better quality of life and better…
BACKGROUNDS/AIMS
The aim of this study was to compare efficacy of two enzymes, Liberase HI and Collagenase XI in human adult…
Objectives: Enzymatic digestion of donor pancreas is a vital step in islet isolation process. Recently, human and large mammalian…
Background. Primary nonfunction resulting in immediate graft loss is responsible for the failure of a large number of islet…
BACKGROUND
Pancreatic islet transplantation (PIT) is an attractive alternative for patients with type I diabetes mellitus. PIT is…