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Liberase

 
National Institutes of Health

Papers overview

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2011
2011
OBJECTIVE To set up a protocol to isolate human preantral follicles with an enzyme produced in good manufacturing practice… Expand
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2010
2010
For more than a decade Liberase HI was commonly used as the standard enzyme blend for clinical human islet isolation until… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND The purpose of this study is to evaluate the effectiveness of a standardized mixture of purified enzymes (Liberase… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Biologic characteristics of enzyme products used for islet isolation are critical for the success of islet… Expand
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Highly Cited
2002
Highly Cited
2002
BACKGROUND A two-layer (University of Wisconsin solution/perfluorochemical [UW/PFC]) cold-storage method delivers sufficient… Expand
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2002
2002
Liberase is a highly purified blend of collagenases that has been specifically developed to eliminate the numerous problems… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Primary nonfunction resulting in immediate graft loss is responsible for the failure of a large number of islet… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Frequent success in human islet isolation is prevented by the large variability of scarce organ donors; this favors… Expand
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1999
1999
To determine the effects of procedural modifications, 23 human islet isolations were analyzed. Isolations were divided into two… Expand
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Highly Cited
1997
Highly Cited
1997
Enzymatic digestion of donor pancreases is a vital step in human and large mammalian islet isolation. The variable enzymatic… Expand
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