Liberase

OBJECTIVE To set up a protocol to isolate human preantral follicles with an enzyme produced in good manufacturing practice… (More)

For more than a decade Liberase HI was commonly used as the standard enzyme blend for clinical human islet isolation until… (More)

OBJECTIVE Enzymatic digestion of the pancreas is a fundamental step in islet isolation and there are many ways to administer the… (More)

BACKGROUND The purpose of this study is to evaluate the effectiveness of a standardized mixture of purified enzymes (Liberase… (More)

OBJECTIVES Enzymatic digestion of donor pancreas is a vital step in islet isolation process. Recently, human and large mammalian… (More)

BACKGROUND Biologic characteristics of enzyme products used for islet isolation are critical for the success of islet… (More)

BACKGROUND Primary nonfunction resulting in immediate graft loss is responsible for the failure of a large number of islet… (More)

INTRODUCTION Islet transplantation is an attractive solution for type I diabetes, but the results are at the present discouraging… (More)

To determine the effects of procedural modifications, 23 human islet isolations were analyzed. Isolations were divided into two… (More)

Enzymatic digestion of donor pancreases is a vital step in human and large mammalian islet isolation. The variable enzymatic… (More)