Liberase
National Institutes of Health
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For more than a decade Liberase HI was commonly used as the standard enzyme blend for clinical human islet isolation until…
BACKGROUND
The purpose of this study is to evaluate the effectiveness of a standardized mixture of purified enzymes (Liberase…
Objective: To determine whether pancreatic islet transplantation can control diabetes and prevent severe life‐threatening…
Background. A two-layer (University of Wisconsin solution/perfluorochemical [UW/PFC]) cold-storage method delivers sufficient…
Background. Primary nonfunction resulting in immediate graft loss is responsible for the failure of a large number of islet…
BACKGROUND
Frequent success in human islet isolation is prevented by the large variability of scarce organ donors; this favors…
Enzymatic digestion of donor pancreases is a vital step in human and large mammalian islet isolation. The variable enzymatic…