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Liberase

National Institutes of Health

Papers overview

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Highly Cited
2012
2010
2010
For more than a decade Liberase HI was commonly used as the standard enzyme blend for clinical human islet isolation until… 
Highly Cited
2006
Highly Cited
2006
BACKGROUND The purpose of this study is to evaluate the effectiveness of a standardized mixture of purified enzymes (Liberase… 
Highly Cited
2006
Highly Cited
2006
Objective: To determine whether pancreatic islet transplantation can control diabetes and prevent severe life‐threatening… 
Highly Cited
2002
Highly Cited
2002
Background. A two-layer (University of Wisconsin solution/perfluorochemical [UW/PFC]) cold-storage method delivers sufficient… 
Highly Cited
2001
Highly Cited
2001
Background. Primary nonfunction resulting in immediate graft loss is responsible for the failure of a large number of islet… 
Highly Cited
1999
Highly Cited
1999
BACKGROUND Frequent success in human islet isolation is prevented by the large variability of scarce organ donors; this favors… 
Highly Cited
1997
Highly Cited
1997
Enzymatic digestion of donor pancreases is a vital step in human and large mammalian islet isolation. The variable enzymatic…