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Liberase

 
National Institutes of Health

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Related topics

3 relations

Broader (2)

COLLAGENASEThermolysin

Narrower (1)

Liberase HI

Papers overview

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2011
2011
Enzymatic isolation of human primordial and primary ovarian follicles with Liberase DH: protocol for application in a clinical setting.
OBJECTIVE To set up a protocol to isolate human preantral follicles with an enzyme produced in good manufacturing practice… Expand
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2010
2010
Large-Scale Comparison of Liberase HI and Collagenase NB1 Utilized for Human Islet Isolation
For more than a decade Liberase HI was commonly used as the standard enzyme blend for clinical human islet isolation until… Expand
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Highly Cited
2006
Highly Cited
2006
Evaluation of Liberase, a purified enzyme blend, for the isolation of human primordial and primary ovarian follicles.
BACKGROUND The purpose of this study is to evaluate the effectiveness of a standardized mixture of purified enzymes (Liberase… Expand
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Highly Cited
2005
Highly Cited
2005
Assessment of a novel two-component enzyme preparation for human islet isolation and transplantation.
BACKGROUND Biologic characteristics of enzyme products used for islet isolation are critical for the success of islet… Expand
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Highly Cited
2002
Highly Cited
2002
Human islet transplantation from pancreases with prolonged cold ischemia using additional preservation by the two-layer (UW solution/perfluorochemical) cold-storage method.
BACKGROUND A two-layer (University of Wisconsin solution/perfluorochemical [UW/PFC]) cold-storage method delivers sufficient… Expand
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2002
2002
Comparison of Size, Viability, and Function of Fetal Pig Islet-Like Cell Clusters after Digestion Using Collagenase or Liberase
Liberase is a highly purified blend of collagenases that has been specifically developed to eliminate the numerous problems… Expand
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Highly Cited
2001
Highly Cited
2001
Endotoxin-mediated delayed islet graft function is associated with increased intra-islet cytokine production and islet cell apoptosis.
BACKGROUND Primary nonfunction resulting in immediate graft loss is responsible for the failure of a large number of islet… Expand
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Highly Cited
1999
Highly Cited
1999
Significant progress in porcine islet mass isolation utilizing liberase HI for enzymatic low-temperature pancreas digestion.
BACKGROUND Frequent success in human islet isolation is prevented by the large variability of scarce organ donors; this favors… Expand
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1999
1999
Improved method for the isolation and purification of human islets of langerhans using Liberase enzyme blend.
To determine the effects of procedural modifications, 23 human islet isolations were analyzed. Isolations were divided into two… Expand
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Highly Cited
1997
Highly Cited
1997
Improved human islet isolation using a new enzyme blend, liberase.
Enzymatic digestion of donor pancreases is a vital step in human and large mammalian islet isolation. The variable enzymatic… Expand
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