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COLLAGENASE

Known as: Collagen Degrading Enzyme, Collagenases [Chemical/Ingredient], Collagenases 
Collagenases are enzymes that degrade collagen fibers. These enzymes play an important role in connective tissue metabolism and are produced by… 
National Institutes of Health

Related topics

Related topics

41 relations
Burn injuryCOLLAGENASE 0.25 UNT/MG Topical OintmentCollagenase:CCnc:Pt:Ser:QnDrug Allergy

Narrower (13)

ColH protein, Clostridium histolyticumFN type IV collagenaseInterstitial CollagenaseLiberase

Broader (4)

GelatinasesMetalloendopeptidasesMetalloproteasesmetalloenzyme

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2000
Highly Cited
2000
Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-Jun N-terminal kinase, and nuclear factor kappaB: differential regulation of…
OBJECTIVE To examine the mechanism of interleukin-1 (IL-1)-induced collagenase 3 (matrix metalloproteinase 13 [MMP-13]) gene… 
Highly Cited
1996
Highly Cited
1996
Biochemical Characterization of Human Collagenase-3 (*)
The cDNA of a novel matrix metalloproteinase, collagenase-3 (MMP-13) has been isolated from a breast tumor library (Freije, J. M… 
Highly Cited
1995
Highly Cited
1995
Mechanism Of Cell Surface Activation Of 72-kDa Type IV Collagenase
Matrix metalloproteases are secreted by mammalian cells as zymogens and, upon activation, initiate tissue remodeling by… 
Highly Cited
1991
Highly Cited
1991
92-kD type IV collagenase mediates invasion of human cytotrophoblasts
The specialized interaction between embryonic and maternal tissues is unique to mammalian development. This interaction begins… 
Highly Cited
1990
Highly Cited
1990
Collagenase-induced intracerebral hemorrhage in rats.
Intracranial bleeding is an important cause of brain masses and edema. To study the pathophysiology of intracerebral hemorrhage… 
Highly Cited
1987
Highly Cited
1987
Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor.
Exposure of quiescent MRC‐5 human fibroblasts to growth factors such as epidermal growth factor, basic fibroblast growth factor… 
Highly Cited
1987
Highly Cited
1987
Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor
Highly Cited
1987
Highly Cited
1987
Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements
Highly Cited
1985
Highly Cited
1985
Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts
Cachectin/TNF (tumor necrosis factor), an endotoxin-induced murine macrophage hormone implicated in the pathogenesis of cachexia… 
Review
1976
Review
1976
Preparation of isolated rat liver cells.
  • P. Seglen
  • Methods in Cell Biology
  • 1976
  • Corpus ID: 36127351
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