Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

COLLAGENASE

Known as: Collagen Degrading Enzyme, Collagenases [Chemical/Ingredient], Collagenases 
Collagenases are enzymes that degrade collagen fibers. These enzymes play an important role in connective tissue metabolism and are produced by… Expand
National Institutes of Health

Related topics

Related topics

41 relations
Burn injuryCOLLAGENASE 0.25 UNT/MG Topical OintmentCollagenase:CCnc:Pt:Ser:QnDrug Allergy
Expand

Narrower (13)

ColH protein, Clostridium histolyticumFN type IV collagenaseInterstitial CollagenaseLiberase
Expand

Broader (4)

GelatinasesMetalloendopeptidasesMetalloproteasesmetalloenzyme

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1996
Highly Cited
1996
Biochemical Characterization of Human Collagenase-3 (*)
The cDNA of a novel matrix metalloproteinase, collagenase-3 (MMP-13) has been isolated from a breast tumor library (Freije, J. M… Expand
  • figure 1
  • figure 2
  • figure 3
  • table I
  • table II
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Mechanism Of Cell Surface Activation Of 72-kDa Type IV Collagenase
Matrix metalloproteases are secreted by mammalian cells as zymogens and, upon activation, initiate tissue remodeling by… Expand
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas.
A cDNA coding for a new human matrix metalloproteinase (MMP) has been cloned from a cDNA library derived from a breast tumor. The… Expand
Is this relevant?
Highly Cited
1993
Highly Cited
1993
Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells.
92-kDa Type IV collagenase, a member of matrix metalloproteinases, is believed to play a critical role in physiological tissue… Expand
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Interaction of 92-kDa type IV collagenase with the tissue inhibitor of metalloproteinases prevents dimerization, complex formation with interstitial collagenase, and activation of the proenzyme with…
Secreted metalloproteases initiating proteolytic degradation of collagens and proteoglycans play a critical role in remodeling of… Expand
Is this relevant?
Highly Cited
1991
Highly Cited
1991
92-kD type IV collagenase mediates invasion of human cytotrophoblasts
The specialized interaction between embryonic and maternal tissues is unique to mammalian development. This interaction begins… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1987
Highly Cited
1987
Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor.
Exposure of quiescent MRC‐5 human fibroblasts to growth factors such as epidermal growth factor, basic fibroblast growth factor… Expand
Is this relevant?
Highly Cited
1985
Highly Cited
1985
Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts
Cachectin/TNF (tumor necrosis factor), an endotoxin-induced murine macrophage hormone implicated in the pathogenesis of cachexia… Expand
  • table I
  • table II
Is this relevant?
Review
1976
Review
1976
Preparation of isolated rat liver cells.
  • P. Seglen
  • Methods in cell biology
  • 1976
    • Corpus ID: 36127351
Publisher Summary This chapter discusses preparation of isolated rat liver cells. The early mechanical and chemical methods for… Expand
Is this relevant?
Highly Cited
1969
Highly Cited
1969
HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLS
A new technique employing continuous recirculating perfusion of the rat liver in situ, shaking of the liver in buffer in vitro… Expand
  • figure 1
  • figure 3
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE