COLLAGENASE

Known as: Collagen Degrading Enzyme, Collagenases [Chemical/Ingredient], Collagenases 
Collagenases are enzymes that degrade collagen fibers. These enzymes play an important role in connective tissue metabolism and are produced by… (More)
National Institutes of Health

Related topics

Related topics

41 relations
Burn injuryCOLLAGENASE 0.25 UNT/MG Topical OintmentCollagenase:CCnc:Pt:Ser:QnDrug Allergy
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Narrower (13)

ColH protein, Clostridium histolyticumFN type IV collagenaseInterstitial CollagenaseLiberase
(More)

Broader (4)

GelatinasesMetalloendopeptidasesMetalloproteasesmetalloenzyme

Papers overview

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Highly Cited
2000
Highly Cited
2000
Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen.
BACKGROUND Registry data on patients with type 1 diabetes mellitus who undergo pancreatic islet transplantation indicate that… (More)
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Highly Cited
1999
Highly Cited
1999
Evidence for increased collagenolysis by interstitial collagenases-1 and -3 in vulnerable human atheromatous plaques.
BACKGROUND Several recent studies attempted to classify plaques as those prone to cause clinical manifestations (vulnerable… (More)
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Highly Cited
1996
Highly Cited
1996
The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes. A role in osteoarthritis.
Recently, a new human collagenase, collagenase-3 has been identified. Since collagen changes are of particular importance in… (More)
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Highly Cited
1995
Highly Cited
1995
The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily.
Tumor cell-derived collagenase stimulatory factor, renamed extracellular matrix metalloproteinase inducer (EMMPRIN), is a M(r… (More)
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Highly Cited
1994
Highly Cited
1994
Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques.
Dysregulated extracellular matrix (ECM) metabolism may contribute to vascular remodeling during the development and complication… (More)
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Highly Cited
1993
Highly Cited
1993
Tumor cell-derived collagenase-stimulatory factor increases expression of interstitial collagenase, stromelysin, and 72-kDa gelatinase.
The tumor cell-derived collagenase-stimulatory factor (TCSF) was previously purified from human lung carcinoma cells (S. M. Ellis… (More)
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Highly Cited
1991
Highly Cited
1991
92-kD type IV collagenase mediates invasion of human cytotrophoblasts
The specialized interaction between embryonic and maternal tissues is unique to mammalian development. This interaction begins… (More)
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Highly Cited
1990
Highly Cited
1990
Collagenase-induced intracerebral hemorrhage in rats.
Intracranial bleeding is an important cause of brain masses and edema. To study the pathophysiology of intracerebral hemorrhage… (More)
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Highly Cited
1989
Highly Cited
1989
Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression
We have investigated the effects of ligation of the fibronectin receptor (FnR) on gene expression in rabbit synovial fibroblasts… (More)
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Highly Cited
1985
Highly Cited
1985
Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts
Cachectin/TNF (tumor necrosis factor), an endotoxin-induced murine macrophage hormone implicated in the pathogenesis of cachexia… (More)
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