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Oocyte vitrification as an efficient option for elective fertility preservation.
TLDR
At least 8-10 metaphase II oocytes are necessary to achieve reasonable success in elective fertility preservation and numbers should be individualized in women >36 years old. Expand
The aromatase inhibitor letrozole increases the concentration of intraovarian androgens and improves in vitro fertilization outcome in low responder patients: a pilot study.
TLDR
Adding 2.5 mg of letrozole to a high-dose FSH/hMG antagonist protocol increases intraovarian androstenedione and T concentration and improves IVF cycle outcome in poor responder patients. Expand
Targeting the vascular endothelial growth factor system to prevent ovarian hyperstimulation syndrome.
TLDR
It is suggested that the syndrome can be prevented by inducing ovulation with LH or GnRH analogues, which prevent VEGF overexpression and co-administration of a dopamine agonist inhibits phosphorylation of the receptor VEGFR-2. Expand
Long-term pituitary down-regulation before in vitro fertilization (IVF) for women with endometriosis.
TLDR
The administration of GnRH agonists for a period of three to six months prior to IVF or ICSI in women with endometriosis increases the odds of clinical pregnancy by fourfold. Expand
Empty follicle syndrome: evidence for recurrence.
TLDR
It is postulate that ovarian ageing, through altered folliculogenesis, may be implicated in the aetiology of EFS and its recurrence and the chances of recurrence increase with the age of the patient. Expand
Ovarian response to recombinant human follicle-stimulating hormone: a randomized, antimüllerian hormone-stratified, dose-response trial in women undergoing in vitro fertilization/intracytoplasmic
TLDR
Examining the dose-response relationship of a novel recombinant human FSH with respect to ovarian response in patients undergoing IVF/intracytoplasmic sperm injection treatment and the influence of initial antimüllerian hormone (AMH) concentrations found a linear increase in number of oocytes retrieved in an AMH-dependent manner. Expand
The endometrium versus embryonic quality in endometriosis-related infertility.
TLDR
The effects of endometriosis at specific stages of the reproductive process including folliculogenesis, fertilization, embryo development and implantation, and recent advances on implantation research show features in the eutopic endometrium of women with endometiosis that are not found in endometium of women without the disease, although there is no agreement on this point. Expand
Comprehensive chromosome screening improves embryo selection: a meta-analysis.
TLDR
PGS with the use of CCS technology increases clinical and sustained IRs, thus improving embryo selection, particularly in patients with normal ovarian reserve, and is associated with a significantly higher clinical IR. Expand
Physiology and pathology of ovarian hyperstimulation syndrome.
TLDR
The pathophysiological mechanisms involved in OHSS show that targeting VEGF/VEGFR2 is an effective preventive approach to treat the syndrome andEmbryo cryopreservation plus dopamine agonist administration might be the most appropriate way to prevent OHSS in high-risk patients. Expand
Sperm cryopreservation in oncological patients: a 14-year follow-up study.
TLDR
A significant number of males who cryopreserved semen samples before receiving antitumoral treatments have employed them, and the results obtained showed that this is the strategy of choice, aiming to preserve fertility for the future, because the cost/benefit ratio is favorable. Expand
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