• Publications
  • Influence
Growth factors in skeletal muscle regeneration.
Adult skeletal muscles are able to regenerate after injury. This process is due to the activation of quiescent muscle precursor cells, also called satellite cells, which proliferate and differentiateExpand
  • 239
  • 14
Heparan Sulfate Is a Cellular Receptor for Purified Infectious Prions*
Prions replicate in the host cell by the self-propagating refolding of the normal cell surface protein, PrPC, into a β-sheet-rich conformer, PrPSc. Exposure of cells to prion-infected material andExpand
  • 157
  • 9
FGF-2 and TPA induce matrix metalloproteinase-9 secretion in MCF-7 cells through PKC activation of the Ras/ERK pathway.
Matrix metalloproteinases (MMPs) play an important role in cancer metastasis. Here, we investigated the effect of fibroblast growth factor-2 (FGF-2) and 12-O-tetradecanoylphorbol-13-acetate (TPA) onExpand
  • 177
  • 8
A Synthetic Glycosaminoglycan Mimetic Binds Vascular Endothelial Growth Factor and Modulates Angiogenesis*
In a previous study, we showed that in situ injection of glycosaminoglycan mimetics called RGTAs® (ReGeneraTing Agents) enhanced neovascularization after skeletal muscular ischemia (Desgranges, P.,Expand
  • 82
  • 7
  • PDF
Immunological study of acidic fibroblast growth factor (aFGF) distribution in the eye
During the last ten years, several groups, including the present authors, have detected growth factor activities in various ocular tissues, and the presence of a ubiquitous Eye‐Derived Growth FactorExpand
  • 103
  • 5
The endogenous oxindoles 5-hydroxyoxindole and isatin are antiproliferative and proapoptotic.
Oxindole-core synthetic molecules are currently being developed as anticancer drugs that target protein tyrosine kinases associated with growth factor receptors. Oxindole, 5-Hydroxyoxindole, and 2,Expand
  • 90
  • 3
Heparin-like polymers derived from dextran enhance colonic anastomosis resistance to leakage.
A new tissue repair agent, RGTA11, is described for its ability to enhance colonic anastomosis repair and resistance to leakage. RGTA11 is a dextran derivative containing 110% carboxymethyl groups,Expand
  • 55
  • 3
Novel heparan mimetics potently inhibit the scrapie prion protein and its endocytosis.
During prion diseases the normal prion protein PrP(C) is refolded into an abnormal conformer PrP(Sc). We have studied the PrP(Sc) inhibiting activity of a library of synthetic heparan mimetic (HM)Expand
  • 79
  • 3
Dominant Negative Effectors of Heparin Affin Regulatory Peptide (HARP) Angiogenic and Transforming Activities*
Heparin affin regulatory peptide (HARP) is an heparin-binding growth factor, highly expressed in several primary human tumors and considered as a rate-limiting angiogenic factor in tumor growth,Expand
  • 29
  • 3
The use of acetone precipitation in the isolation of ribosomal proteins.
Acetone precipitation is a rapid and efficient method for concentrating ribosomal proteins. This procedure also permits the elimination of sodium dodecylsulphate or urea from protein solutionsExpand
  • 153
  • 2