Skip to search formSkip to main contentSkip to account menu

Thalicarpine

Known as: 4H-dibenzo[de,g]quinoline, 9-[4, 5-dimethoxy-2-[(1,2,3,4-tetrahydro-6, 7-dimethoxy-2-methyl-1-isoquinolinyl)methyl]phenoxy]-5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, [S-(R*,R*)]- (9CI), [S-(R*,R*)]-9-[4,5-dimethoxy-2-[(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)-methyl]phenoxy]-5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinoline, 6a-Alpha-aporphine, 9-[[4,5-dimethoxy-alpha-((S)-1,2,3, 4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolyl)-o-tolyl]oxy]-1, 2,10-trimethoxy- 
A natural aporphine benzylisoquinoline vinca alkaloid with antineoplastic activity. Thalicarpine binds to and inhibits p-glycoprotein, the multidrug… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (1)

Aporphines
Microtubule ProcessNCIt Antineoplastic Agent Terminology

Narrower (1)

Thaliblastine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Synthetic Oxoisoaporphine Alkaloids: In Vitro, In Vivo and In Silico Assessment of Antileishmanial Activities
Leishmaniasis is a growing health problem worldwide. As there are certain drawbacks with the drugs currently used to treat human… 
2007
2007
Aporphine metho salts as neuronal nicotinic acetylcholine receptor blockers.
2003
2003
First total syntheses of the 1,2,3,4-tetrahydronaphtho[2,1-f]isoquinolines annoretine and litebamine
Highly Cited
1997
Highly Cited
1997
Inhibition of Eukaryote Protein Kinases by Isoquinoline and Oxazine Alkaloids
O 
1997
1997
Inhibition of Tyrosine Hydroxylase by Bulbocapnine
L K 
1992
1992
Antitumor activity of thaliblastine (NSC-68075) in experimental ovarian tumor cell lines sensitive and resistant to cisplatin.
1980
1980
On the ability of N‐chloroethyl aporphine derivatives to cause irreversible inhibition of dopamine receptor mechanisms
The potential dopamine inhibitory properties of (‐)N‐(2‐chloroethyl)‐norapomorphine [(‐)NCA], (‐)N‐(hydroxyethyl)norapomorphine… 
1979
1979
Dimeric Aporphine-Benzylisoquinoline and Aporphine-Pavine Alkaloids.
1978
1978
Alkaloids of Thalictrum XXVII. New hypotensive aporphine-benzylisoquinoline derived dimeric alkaloids from Thalictrum minus race B.
The roots of T. minus race B have yielded, in addition to adiantifoline (1) previously isolated from this source, two new related… 
1968
1968
Ocotea alkaloids: the chaacterization and structures of four new aporphine bases.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)