• Publications
  • Influence
Randomized, multicenter, dose-ranging trial of retigabine for partial-onset seizures
TLDR
Adjunctive therapy with retigabine is well tolerated and reduces the frequency of partial-onset seizures in a dose-dependent manner.
Efficacy and safety of adjunctive ezogabine (retigabine) in refractory partial epilepsy
TLDR
In this dose-ranging, placebo-controlled trial, adjunctive EZG (RTG) was effective and generally well tolerated in adults with refractory partial-onset seizures.
Randomized, double-blind, placebo-controlled trial of ezogabine (retigabine) in partial epilepsy
TLDR
This study demonstrates that EZG(RTG) 1,200 mg/day is effective as add-on therapy for reducing seizure frequency in patients with drug-resistant partial-onset seizures.
Magnetic Resonance Imaging Evidence of Hippocampal Sclerosis in Progression: A Case Report
  • V. Nohria, Namsoo Lee, +7 authors D. Lewis
  • Psychology, Medicine
    Epilepsia
  • 1 November 1994
TLDR
It is demonstrated that acute increased hippocampal T2 signal intensity can occur soon after status epilepticus and hippocampal sclerosis (HS) may become evident within months in the setting of recurrent early childhood SE.
Climbing behaviour induced by apomorphine in mice: a potential model for the detection of neuroleptic activity.
TLDR
Differences are discussed in terms of differential abilities to induce extrapyramidal disturbances and the mouse climbing model is forwarded as a test with potential to detect antipsychotic agents of different activity spectra.
Inhibition of TGF-beta2 with AP 12009 in recurrent malignant gliomas: from preclinical to phase I/II studies.
TLDR
Results implicate targeted TGF-beta2-suppression using AP 12009 as a promising novel approach for malignant gliomas and other highly aggressive, T GF-beta-2-overexpressing tumors.
Comparison of the doubly labeled water (2H2(18)O) method with indirect calorimetry and a nutrient-balance study for simultaneous determination of energy expenditure, water intake, and metabolizable
TLDR
It is indicated that the doubly labeled water method can provide accurate information on rates of CO2 production, energy expenditure, and water intake in preterm infants, but individual estimates of ME intake may be subject to substantial error.
Inhibition of TGF-β2 with AP 12009 in Recurrent Malignant Gliomas: From Preclinical to Phase I/II Studies
TLDR
Results implicate targeted TGF-beta2-suppression using AP 12009 as a promising novel approach for malignant gliomas and other highly aggressive, T GF-beta-2-overexpressing tumors.
Chiari I malformation: a review of 43 patients.
TLDR
It was able to show the patients who did not have hydrosyringomyelia were unlikely to develop scoliosis and there was positive correlation between improvement in hydrosyringsomyelia and the improvement in signs and symptoms.
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