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Thaliblastine

Known as: Taliblastine 
National Institutes of Health

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Thalicarpine

Papers overview

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2005
2005
Antiproliferative activity of the non-myelotoxic antitumour agent of plant origin, Thaliblastine, on two human glioma cell lines
SummaryThe antiproliferative activity of the non-myelotoxic antitumour agent of plant origin, Thaliblastine, on two human glioma… 
2005
2005
Cell cycle effects of thaliblastine
The non-myelotoxic antitumor drug thaliblastine (thalicarpine, NSC-68075, CAS-5373-42-21) has a novel chemical structure; it is a… 
1996
1996
Differential interactions of Pgp inhibitor thaliblastine with adriamycin, etoposide, taxol and anthrapyrazole CI941 in sensitive and multidrug-resistant human MCF-7 breast cancer cells.
The reversing effect of p-glycoprotein (Pgp) inhibitors on the multidrug resistance (MDR) phenotype is well established in a… 
1995
1995
Complete reversal by thaliblastine of 490-fold adriamycin resistance in multidrug-resistant (MDR) human breast cancer cells. Evidence that multiple biochemical changes in MDR cells need not…
The emergence of drug resistance is a major obstacle to effective cancer chemotherapy. The identification of novel agents that… 
1993
1993
Thaliblastine, a plant alkaloid, circumvents multidrug resistance by direct binding to P-glycoprotein.
The effect of thaliblastine (TBL, NSC-68075), a plant alkaloid, in over-coming multidrug resistance was investigated in… 
1993
1993
Collateral sensitivity to thaliblastine and/or hyperthermia exhibited by a rat ovarian tumor cell line selected for resistance to cisplatin.
Drug resistance severely limits the effectiveness of clinical cancer chemotherapy. Employment of drugs other than the selected… 
1982
1982
Incorporation of the antitumor alkaloid thaliblastine in liposomes enhances its cytotoxic activity in vitro
The incorporation of the antitumor alkaloid thaliblastine in liposomes greatly enhances its cytotoxicity in Walker S and TLX-5… 
1980
1980
Enhancement of antitumor effect of cyclophosphamide by thaliblastine in Lewis lung carcinoma and L1210 leukemia in mice.
Cyclophosphamide (CY) was tested in combination with the thalictrum alkaloid named thaliblastine (TBL) for therapeutic activity… 
1977
1977
[Toxicological characteristics of thaliblastine[].
The toxic action of the antiphlogistic drug thaliblastin, containing 93-95 per cent of the alcaloid thalicarpine was investigated… 
1976
1976
Effect of thaliblastine on transplantable tumours in mice.
The antitumour activity of the alkaloid thaliblastine was studied on 7 ascitic and solid transplantable tumours in mice. It was… 
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