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Tacrolimus Binding Proteins

Known as: Protein, FK-506-Binding, FK 506 Binding Protein, FK-506-Binding Protein 
A family of immunophilin proteins that bind to the immunosuppressive drugs TACROLIMUS (also known as FK506) and SIROLIMUS. EC 5.2.1.-
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
BackgroundThere is a rapidly increasing amount of de novo genome assembly using next-generation sequencing (NGS) short reads… 
Highly Cited
2011
Highly Cited
2011
Advanced age is the main risk factor for most chronic diseases and functional deficits in humans, but the fundamental mechanisms… 
Highly Cited
2000
Highly Cited
2000
Dysregulated signal transduction from receptor tyrosine kinases to phosphatidylinositol 3-kinase (PI3K), AKT (protein kinase B… 
Highly Cited
1995
Highly Cited
1995
Enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli O157:H7 are intestinal pathogens that profoundly damage… 
Highly Cited
1994
Highly Cited
1994
THE structurally related natural products rapamycin and FK506 bind to the same intracellular receptor, FKBP12, yet the resulting… 
Highly Cited
1992
Highly Cited
1992
Loss of telomeric DNA during cell proliferation may play a role in ageing and cancer. Since telomeres permit complete replication… 
Highly Cited
1991
Highly Cited
1991
FK506 and rapamycin are related immunosuppressive compounds that block helper T cell activation by interfering with signal… 
Review
1985
Review
1985
Epstein–Barr virus (EBV) infects human B lymphocytes, transforming the infected cells into dividing blasts that can proliferate…