FKBP1A protein, human

Known as: EC 5.2.1.8, Peptidyl-Prolyl Cis-Trans Isomerase FKBP1A, Immunophilin FKBP12 
Peptidyl-prolyl cis-trans isomerase FKBP1A (108 aa, ~12 kDa) is encoded by the human FKBP1A gene. This protein is involved in both protein folding… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1991-2010
0246819912010

Papers overview

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1997
1997
The immunosuppressant drugs FK506 and cyclosporin A inhibit T-cell proliferation via a common mechanism: calcineurin inhibition… (More)
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1996
Highly Cited
1996
The immunophilin FKBP12 is an evolutionarily conserved abundant protein; however, its physiological roles remain poorly defined… (More)
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1995
1995
FKBP-12 (FKBP), the soluble receptor for the immunosuppresant drug FK-506, is tightly bound to the calcium release channel (CRC… (More)
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1995
1995
Immunophilins are a group of proteins that serve as receptors for the immunosuppressant drugs cyclosporin A and FK506. The… (More)
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Highly Cited
1994
Highly Cited
1994
Transforming growth factor-beta (TGF-beta) family members bind to receptors that consist of heteromeric serine-threonine kinase… (More)
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1994
1994
Parallel measurements of the thermodynamics (free-energy, enthalpy, entropy and heat-capacity changes) of ligand binding to FK506… (More)
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1994
1994
The calcium release channel/ryanodine receptor of rabbit skeletal muscle sarcoplasmic reticulum is tightly associated with the… (More)
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Highly Cited
1993
Highly Cited
1993
High resolution structures for the complexes formed by the immunosuppressive agents FK506 and rapamycin with the human… (More)
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1992
1992
FK-506 inhibits Ca(2+)-dependent transcription of lymphokine genes in T cells, and thereby acts as a powerful immunosuppressant… (More)
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1991
1991
The 12-kDa FK506-binding protein (FKBP-12) is a cytosolic receptor for the immunosuppressants FK506 and rapamycin. Here we report… (More)
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