Skip to search formSkip to main contentSkip to account menu

FKBP1A protein, human

Known as: EC 5.2.1.8, Peptidyl-Prolyl Cis-Trans Isomerase FKBP1A, Immunophilin FKBP12 
Peptidyl-prolyl cis-trans isomerase FKBP1A (108 aa, ~12 kDa) is encoded by the human FKBP1A gene. This protein is involved in both protein folding… 
National Institutes of Health

Related topics

Related topics

10 relations
Cytoplasmic matrixEnzyme GeneFKBP1A geneFKBP1A wt Allele

Broader (1)

Tacrolimus Binding Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Polymorphisms in mTOR and Calcineurin Signaling Pathways Are Associated With Long-Term Clinical Outcomes in Kidney Transplant Recipients
Monitoring of immunosuppressive drugs, such as calcineurin and mTOR inhibitors, is essential to avoid undesirable kidney… 
2009
2009
NO may prompt calcium leakage in dystrophic muscle
A remote, downstream event in the pathology of muscular dystrophy may have a key role in the disease (pages 325–330). It seems… 
2007
2007
Multimer formation by FKBP‐12: roles for cysteine 23 and phenylalanine 36
FKBP‐12 mediates the immunosuppressive actions of FK506 and rapamycin, and modulates the activities of the ryanodine, IP3 and… 
Highly Cited
2005
Highly Cited
2005
Enhancing calstabin binding to ryanodine receptors improves cardiac and skeletal muscle function in heart failure.
Review
1999
Review
1999
Sarcoplasmic reticulum in aged skeletal muscle.
A decrease in muscle mass and strength and a slowing of muscle contraction are common features of the ageing process. Recent… 
Highly Cited
1994
Highly Cited
1994
Specific interaction of type I receptors of the TGF-beta family with the immunophilin FKBP-12.
Transforming growth factor-beta (TGF-beta) family members bind to receptors that consist of heteromeric serine-threonine kinase… 
1994
1994
Streptomyces chrysomallus FKBP‐33 is a novel immunophilin consisting of two FK506 binding domains; its gene is transcriptionally coupled to the FKBP‐12 gene.
The nucleotide sequence of the region 5′ to the fkbA gene, encoding the Streptomyces chrysomallus FK506 binding protein (FKBP‐12… 
1994
1994
Solution structure of FK506 bound to the R42K, H87V double mutant of FKBP-12.
The binding of the FK506/FKBP-12 complex to calcineurin (CN), its putative target for immunosuppression, involves recognition of… 
1992
1992
Saccharomyces cerevisiae contains a homolog of human fkbp‐13, a membrane‐associated fk506/rapamycin binding protein
Highly Cited
1992
Highly Cited
1992
Calcineurin mediates inhibition by FK506 and cyclosporin of recovery from α-factor arrest in yeast
THE structurally unrelated immunosuppressants FK506 and cyclosporin A (CsA) act similarly, inhibiting a Ca2+-dependent signal… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)