FKBP1A gene

Known as: FK506-BINDING PROTEIN, 12-KD, FK506-BINDING PROTEIN 1, FKBP1A 
This gene is involved in both signaling and protein folding.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2017
051019752017

Papers overview

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2011
2011
PURPOSE Malignant peripheral nerve sheath tumors (MPNST) are highly aggressive sarcomas with variable patient survival and few… (More)
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Highly Cited
2009
Highly Cited
2009
Memory CD8 T cells are a critical component of protective immunity, and inducing effective memory T-cell responses is a major… (More)
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Highly Cited
2005
Highly Cited
2005
The macrolide rapamycin specifically binds the 12-kD FK506-binding protein (FKBP12), and this complex potently inhibits the… (More)
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Highly Cited
1996
Highly Cited
1996
The immunophilin FKBP12 is an evolutionarily conserved abundant protein; however, its physiological roles remain poorly defined… (More)
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Highly Cited
1995
Highly Cited
1995
The antifungal, immunosuppressive compound rapamycin arrests the cell cycle in G1 in both yeast cells and T-lymphocytes. Previous… (More)
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1995
1995
FKBP-12 (FKBP), the soluble receptor for the immunosuppresant drug FK-506, is tightly bound to the calcium release channel (CRC… (More)
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Highly Cited
1994
Highly Cited
1994
Simultaneous recordings were made from large ensembles of hippocampal "place cells" in three rats during spatial behavioral tasks… (More)
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Highly Cited
1994
Highly Cited
1994
Transforming growth factor-beta (TGF-beta) family members bind to receptors that consist of heteromeric serine-threonine kinase… (More)
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Highly Cited
1993
Highly Cited
1993
High resolution structures for the complexes formed by the immunosuppressive agents FK506 and rapamycin with the human… (More)
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1992
1992
THE structurally unrelated immunosuppressants FK506 and cyclosporin A (CsA) act similarly, inhibiting a Ca2+-dependent signal… (More)
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