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FKBP2 gene

Known as: FK506-BINDING PROTEIN 2, PPIase, FK506-BINDING PROTEIN, T-CELL, 13-KD 
 
National Institutes of Health

Related topics

Related topics

8 relations
FKBP-13FKBP1A geneFKBP1B geneFKBP3 gene
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Broader (1)

Genes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
The Activity and Specificity of the Outer Membrane Protein Chaperone SurA Are Modulated by a Proline Isomerase Domain
ABSTRACT SurA is a component of the periplasmic chaperone network that plays a central role in biogenesis of integral outer… Expand
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2012
2012
The TLR7/8 Agonist CL097 Primes N-Formyl-Methionyl-Leucyl-Phenylalanine–Stimulated NADPH Oxidase Activation in Human Neutrophils: Critical Role of p47phox Phosphorylation and the Proline Isomerase…
Superoxide anion production by the neutrophil NADPH oxidase plays a key role in host defense; however, excessive superoxide… Expand
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Highly Cited
2010
Highly Cited
2010
The PHD3 Domain of MLL Acts as a CYP33-Regulated Switch between MLL-Mediated Activation and Repression†,
The mixed lineage leukemia (MLL) gene plays a critical role in epigenetic regulation of gene expression and is a frequent target… Expand
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Highly Cited
2009
Highly Cited
2009
Hidden alternate structures of proline isomerase essential for catalysis
A long-standing challenge is to understand at the atomic level how protein dynamics contribute to enzyme catalysis. X-ray… Expand
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Highly Cited
2006
Highly Cited
2006
Proline Isomerization of Histone H3 Regulates Lysine Methylation and Gene Expression
The cis-trans isomerization of proline serves as a regulatory switch in signaling pathways. We identify the proline isomerase… Expand
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Highly Cited
2005
Highly Cited
2005
The FK506 Binding Protein Fpr3 Counteracts Protein Phosphatase 1 to Maintain Meiotic Recombination Checkpoint Activity
The meiotic recombination checkpoint delays gamete precursors in G2 until DNA breaks created during recombination are repaired… Expand
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Highly Cited
1993
Highly Cited
1993
The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae.
The immunosuppressants cyclosporin A, FK506, and rapamycin inhibit growth of unicellular eukaryotic microorganisms and also block… Expand
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1993
1993
The FKB2 gene of Saccharomyces cerevisiae, encoding the immunosuppressant-binding protein FKBP-13, is regulated in response to accumulation of unfolded proteins in the endoplasmic reticulum.
The FKB2 gene of Saccharomyces cerevisiae encodes a homolog of mammalian FKBP-13, an FK506/rapamycin-binding protein that… Expand
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1992
1992
The Hsp56 component of steroid receptor complexes binds to immobilized FK506 and shows homology to FKBP-12 and FKBP-13.
Extracts from human Jurkat cells or from calf thymus contain a 60-kDa protein that is bound to immobilized FK506. As expected… Expand
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Highly Cited
1991
Highly Cited
1991
Folding of influenza hemagglutinin in the endoplasmic reticulum
The folding of influenza hemagglutinin (HA0) in the ER was analyzed in tissue culture cells by following the formation of… Expand
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