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TYMS gene
Known as:
dTMP SYNTHASE
, HsT422
, TYMS
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This gene is involved in DNA replication and repair.
National Institutes of Health
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Related topics
Related topics
6 relations
DNA Repair
DNA Replication
Methylation
Nucleotide Metabolism
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Аллельные полиморфизмы гена тимидилатсинтазы и их гаплотипы как предикторы ответа на метотрексат у больных ревматоидным артритом
И. В. Девальд
,
Е. А. Ходус
,
Е. Б. Хромова
,
О. Б. Несмеянова
,
Александра Леонидовна Бурмистрова
2019
Corpus ID: 198254826
Methotrexate (MT) is recognized as the main component of the treat to target strategy in patients with rheumatoid arthritis (RA…
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2018
2018
TMS: nova nada u liječenju Alzheimerove demencije
Aida Križaj Grden
,
N. Mimica
2018
Corpus ID: 127277446
2017
2017
Distribution of the most common polymorphisms in TYMS gene in Slavic population of central Europe.
A. Pastorakova
,
D. Chandogova
,
+7 authors
R. Petrovič
Neoplasma (Bratislava)
2017
Corpus ID: 9233742
Thymidylate synthetase (TS) plays a critical role in the de novo synthesis of dTMP inside the cell. Therefore, TS is a suitable…
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2016
2016
Converging evolutionary, environmental and clinical ideas on folate metabolism
Patrice Jones
,
E. Beckett
,
Z. Yates
,
M. Veysey
,
M. Lucock
2016
Corpus ID: 56473659
Folate is a UV-labile vitamin, critical to maintenance of DNA synthesis and repair mechanisms. Evidence supports a number of…
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2006
2006
Fourteen novel genetic variations and haplotype structures of the TYMS gene encoding human thymidylate synthase (TS).
Su-ryang Kim
,
S. Ozawa
,
+11 authors
J. Sawada
Drug Metabolism and Pharmacokinetics
2006
Corpus ID: 6808600
Forty genetic variations including 14 novel ones were found in the human TYMS gene, which encodes thymidylate synthase, in 263…
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1999
1999
MDR1 and thymidylate synthase (TS) gene expressions in advanced breast cancer: relationships to drug exposure, p53 mutations, and clinical outcome of the patients.
S. Lizard‐Nacol
,
P. Genne
,
+5 authors
P. Fargeot
Anticancer Research
1999
Corpus ID: 8234820
To characterize the biological features of advanced breast cancer associated with poor chemotherapy response and worse prognosis…
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1986
1986
Organization of the thymidylate synthase gene of herpesvirus saimiri
W. Bodemer
,
H. Niller
,
N. Nitsche
,
B. Scholz
,
B. Fleckenstein
Journal of Virology
1986
Corpus ID: 23844032
Herpesvirus saimiri codes, unlike most other herpesviruses, for a thymidylate synthase (TS). The TS gene of herpesvirus saimiri…
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1986
1986
Induction, by thymidylate stress, of genetic recombination as evidenced by deletion of a transferred genetic marker in mouse FM3A cells
D. Ayusawa
,
H. Koyama
,
K. Shimizu
,
S. Kaneda
,
K. Takeishi
,
T. Seno
Molecular and Cellular Biology
1986
Corpus ID: 9451744
Studies were made on the genetic consequences of methotrexate-directed thymidylate stress, focusing attention on a human…
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1986
1986
Mouse thymidylate synthase messenger RNA lacks a 3' untranslated region.
C. Jenh
,
T. Deng
,
D. Li
,
J. Dewille
,
L. Johnson
Proceedings of the National Academy of Sciences…
1986
Corpus ID: 20516742
Analysis of the sequence of cDNA corresponding to mouse thymidylate synthase (5,10-methylenetetrahydrofolate:dUMP C…
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1985
1985
Antiviral activity of 2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl-5-iodocytosine against human cytomegalovirus in human skin fibroblasts
J. Colacino
,
C. López
Antimicrobial Agents and Chemotherapy
1985
Corpus ID: 38101368
2'-Deoxy-2'-fluoro-beta-D-arabinofuranosyl-5-iodocytosine (FIAC) was shown to be a selective anti-human cytomegalovirus agent in…
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