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TYK2 Kinase

Known as: TYK2 Kinase [Chemical/Ingredient], Non Receptor Tyrosine Protein Kinase TYK2, Non-Receptor Tyrosine-Protein Kinase TYK2 
A Janus kinase subtype that is involved in signaling from a broad variety of CYTOKINE RECEPTORS. The TYK2 kinase is considered the founding member of… 
National Institutes of Health

Related topics

Related topics

12 relations
In BloodJAK2 protein, humanProcess of secretionTYK2 gene

Broader (1)

Janus kinase

Narrower (1)

Tyrosine Kinase 2 Deficiency

Papers overview

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2011
2011
Non-Overlapping Functions for Pyk2 and FAK in Osteoblasts during Fluid Shear Stress-Induced Mechanotransduction
Mechanotransduction, the process by which cells convert external mechanical stimuli such as fluid shear stress (FSS) into… 
Highly Cited
2005
Highly Cited
2005
Dengue virus type 2 antagonizes IFN-alpha but not IFN-gamma antiviral effect via down-regulating Tyk2-STAT signaling in the human dendritic cell.
The immunopathogenesis mechanism of dengue virus (DV) infection remains elusive. We previously showed that the target of DV in… 
2004
2004
Control of Leishmania major in the absence of Tyk2 kinase
IL‐12 is indispensable for the control of many intracellular pathogens, but the components of the signaling pathway that are… 
Highly Cited
2002
Highly Cited
2002
Vasopressin-mediated mitogenic signaling in intestinal epithelial cells.
The role of G protein-coupled receptors and their ligands in intestinal epithelial cell signaling and proliferation is poorly… 
Highly Cited
2001
Highly Cited
2001
Cocaine-responsive gene expression changes in rat hippocampus
Highly Cited
2000
Highly Cited
2000
Urokinase Stimulates Human Vascular Smooth Muscle Cell Migration via a Phosphatidylinositol 3-Kinase-Tyk2 Interaction*
Janus kinases Jak1 and Tyk2 play an important role in urokinase-type plasminogen activator (uPA)-dependent signaling. We have… 
Review
1999
Review
1999
Janus kinases and their role in growth and disease.
Highly Cited
1999
Highly Cited
1999
Kaposi's Sarcoma-associated Herpesvirus-encoded G Protein-coupled Receptor Activation of c-Jun Amino-terminal Kinase/Stress-activated Protein Kinase and Lyn Kinase Is Mediated by Related Adhesion…
The Kaposi's sarcoma-associated herpesvirus (KSHV) (also known as human herpesvirus 8) has been implicated in the pathogenesis of… 
Highly Cited
1994
Highly Cited
1994
p135tyk2, an interferon-alpha-activated tyrosine kinase, is physically associated with an interferon-alpha receptor.
Highly Cited
1994
Highly Cited
1994
JAK3 Janus kinase is involved in interleukin 7 signal pathway
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