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TYK2 Kinase

Known as: TYK2 Kinase [Chemical/Ingredient], Non Receptor Tyrosine Protein Kinase TYK2, Non-Receptor Tyrosine-Protein Kinase TYK2 
A Janus kinase subtype that is involved in signaling from a broad variety of CYTOKINE RECEPTORS. The TYK2 kinase is considered the founding member of… 
National Institutes of Health

Related topics

Related topics

12 relations
In BloodJAK2 protein, humanProcess of secretionTYK2 gene

Broader (1)

Janus kinase

Narrower (1)

Tyrosine Kinase 2 Deficiency

Papers overview

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2017
2017
Adenovirus Vector Harboring the HBcAg and Tripeptidyl Peptidase II Genes Induces Potent Cellular Immune Responses In Vivo
Background: Chronic hepatitis B virus (HBV) infection is associated with a weak but specific cellular immune response of the host… 
2015
2015
Activation of the GP 130-STAT 3 axis and its potential implications in nonalcoholic fatty liver disease
Hae-Ki Min,* Faridoddin Mirshahi, Aurora Verdianelli, Tommy Pacana, Vaishali Patel, Chun-Geon Park, Aejin Choi, Jeong-Hoon Lee… 
2012
2012
Genetics of Psoriasis and Psoriatic Arthritis: A Report from the GRAPPA 2010 Annual Meeting
Psoriasis vulgaris (PsV) and psoriatic arthritis (PsA) are interrelated disorders, PsA representing a disease within a disease… 
2011
2011
Molecular Pharmacology Fast Forward
1 Title: Abelson family tyrosine kinases regulate the function of nicotinic acetylcholine receptors and nicotinic synapses on… 
2011
2011
Sarcoidosis is a Th1/Th17 multisystem disorder: wider implications
Facco et al demonstrated elevated levels of T helper 17 (Th17) cells in the peripheral blood and in the bronchoalveolar lavage of… 
2008
2008
Tumor-induced suppressor of cytokine signaling 3 inhibits toll-like receptor 3 signaling in dendritic cells via binding to tyrosine kinase 2.
The suppressor of cytokine signaling (SOCS) family of negative regulatory proteins is up-regulated in response to several… 
2008
2008
A dose-escalation and pharmacodynamic study of AT9283 in patients with refractory solid tumours
2519 Background: AT9283, a multitargeted kinase inhibitor, inhibits tyrosine and serine/threonine kinases with an IC50 of <10 nM… 
2004
2004
Differential regulation of cell migration and proliferation through proline-rich tyrosine kinase 2 in endothelial cells.
Proline-rich tyrosine kinase 2 (Pyk2), a member of the focal adhesion kinase family, is thought to act as a key component in… 
2003
2003
Differential requirements for JAK2 and TYK2 in T cell proliferation and IFN-γ production induced by IL-12 alone or together with IL-18
2001
2001
Regulation of STAT protein synthesis by c-Cbl
Many cytokines and growth factors induce transcription of immediate early response genes by activating members of the Signal… 
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