TYK2 gene

Known as: TYROSINE KINASE 2, JTK1, TYK2 
This gene is involved in both protein phosphorylation and interferon-mediated signaling.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
05101519902018

Papers overview

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2016
2016
BACKGROUND Recurrence and/or metastasis occurs in more than half of patients with head and neck squamous cell carcinoma (HNSCC… (More)
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2015
2015
Pancreatic β-cells are destroyed by an autoimmune attack in type 1 diabetes. Linkage and genome-wide association studies point to… (More)
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2013
2013
Constitutively-activated JAK/Stat3 or Src/Stat3 signaling plays a crucial role in tumor cell survival, proliferation… (More)
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2012
2012
Our previous report showed that platelet-derived growth factor (PDGF) and related genes were upregulated in a Syrian hamster… (More)
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2011
2011
Interleukin-17A (IL-17A)-producing γδ T cells differentiate in the fetal thymus and reside in the peripheral tissues, such as the… (More)
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Highly Cited
2009
Highly Cited
2009
In a recent genome-wide association study (GWAS) based on 12 374 non-synonymous single nucleotide polymorphisms we identified a… (More)
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2007
2007
OBJECTIVES This is a family-based association study to investigate the genetic contribution of tyrosine kinase 2 (TYK2 ) to… (More)
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2007
2007
The effects of 2-naphthylethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (THI 53), on nitric oxide (NO) production and… (More)
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Highly Cited
2005
Highly Cited
2005
Systemic lupus erythematosus (SLE) is a complex systemic autoimmune disease caused by both genetic and environmental factors… (More)
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2001
2001
Osteoclast activation is initiated by adhesion to bone, cytoskeletal rearrangement, formation of the sealing zone, and formation… (More)
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