Skip to search formSkip to main contentSkip to account menu

TRYPTASE

Known as: lung tryptase, Tryptases [Chemical/Ingredient], EC 3.4.21.59 
A family of serine endoproteinases usually expressed in mast cell secretory granules. These enzymes cleave protein substrates after arginine or… 
National Institutes of Health

Related topics

Related topics

20 relations
In BloodPeptidase GeneProcess of secretionProteolysis

Narrower (6)

Mcpt8 protein, mouseTryptase Beta-2, humanalpha-Tryptasesbeta-Tryptases

Broader (1)

Serine Proteases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Specific immunoglobulin E for staphylococcal enterotoxins in nasal polyps from patients with aspirin‐intolerant asthma
Background Nasal polyps infiltrated with eosinophils are commonly found in chronic asthmatic patients, more frequently in those… 
Review
2002
Review
2002
New developments in the genetics and activation of mast cell proteases.
Highly Cited
2000
Highly Cited
2000
Characterization of Human γ-Tryptases, Novel Members of the Chromosome 16p Mast Cell Tryptase and Prostasin Gene Families1
Previously, this laboratory identified clusters of α-, β-, and mast cell protease-7-like tryptase genes on human chromosome 16p13… 
Highly Cited
1999
Highly Cited
1999
Grass pollen immunotherapy decreases the number of mast cells in the skin
Allergen injection immunotherapy is effective for summer hay fever and reduces cutaneous sensitivity to grass pollen. 
Highly Cited
1997
Highly Cited
1997
Mast cell tryptase potentiates histamine-induced contraction in human sensitized bronchus.
The mast cell plays a pivotal role in the early asthmatic response via release of mediators, which directly influence airway… 
Highly Cited
1990
Highly Cited
1990
Cloning and characterization of a second complementary DNA for human tryptase.
A second cDNA for human tryptase, called beta-tryptase, was cloned from a mast cell cDNA library in lambda ZAP. Its nucleotide… 
Highly Cited
1985
Highly Cited
1985
The fibrinogenolytic activity of purified tryptase from human lung mast cells.
The capacity of purified tryptase from human lung mast cells to metabolize human fibrinogen, fibrin, and plasminogen was… 
Highly Cited
1985
Highly Cited
1985
Chymotrypsin- and trypsin-type serine proteases in rat mast cells: properties and functions.
Highly Cited
1983
Highly Cited
1983
Generation of C3a anaphylatoxin from human C3 by human mast cell tryptase.
Tryptase, the dominant neutral protease of human pulmonary mast cell secretory granules, has the capacity in vitro to generate… 
Highly Cited
1983
Highly Cited
1983
Inactivation of human high molecular weight kininogen by human mast cell tryptase.
Tryptase, the major neutral protease of human pulmonary mast cell secretory granules, rapidly inactivates human high m.w… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)