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TRYPTASE

Known as: lung tryptase, Tryptases [Chemical/Ingredient], EC 3.4.21.59 
A family of serine endoproteinases usually expressed in mast cell secretory granules. These enzymes cleave protein substrates after arginine or… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
This review presents evidence that the skin mast cell, in particular the MCTC subtype, is the primary effector cell in urticaria… Expand
Review
2006
Review
2006
  • L. Schwartz
  • Immunology and allergy clinics of North America
  • 2006
  • Corpus ID: 18733953
Serum (or plasma) levels of total and mature tryptase measurements are recommended in the diagnostic evaluation of systemic… Expand
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Highly Cited
2005
Highly Cited
2005
Tight junctions between intestinal epithelial cells prevent ingress of luminal macromolecules and bacteria and protect against… Expand
Highly Cited
1997
Highly Cited
1997
Tryptase is a serine protease secreted by mast cells that is able to activate other cells. In the present studies we have tested… Expand
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  • table I
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Highly Cited
1997
Highly Cited
1997
The presence of mast cells near capillary sprouting sites suggests an association between mast cells and angiogenesis. However… Expand
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Highly Cited
1997
Highly Cited
1997
Mast cell activation is a characteristic feature of chronic inflammation, a condition that may lead to fibrosis as a result of… Expand
  • figure 1
  • table I
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  • figure 2
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Highly Cited
1989
Highly Cited
1989
Tryptase, a neutral protease of human mast cells, is a potentially important indicator of mast cell involvement in various… Expand
  • figure 2
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  • table I
  • figure 4
Highly Cited
1989
Highly Cited
1989
Mast cells have been implicated in the pathogenesis of the matrix degradation observed in the cartilaginous and osseous… Expand
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Highly Cited
1987
Highly Cited
1987
Better methods are needed to assess mast-cell activation in vivo and to distinguish the activation of mast cells from that of… Expand
Highly Cited
1987
Highly Cited
1987
Levels of histamine, chymase, and tryptase were assessed in preparations of dispersed human TC (tryptase+, chymase+) mast cells… Expand