TRYPTASE

Known as: lung tryptase, Tryptases [Chemical/Ingredient], EC 3.4.21.59 
A family of serine endoproteinases usually expressed in mast cell secretory granules. These enzymes cleave protein substrates after arginine or… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1946-2017
05010015019462016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Since serum tryptase levels are elevated in some patients with myeloproliferative disorders, we examined their utility in… (More)
  • table 1
  • figure 1
  • table 3
  • table 2
  • figure 2
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Mast-cell products can stimulate fibroblast proliferation, implying that these cells are key players in fibrosis. One mast-cell… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 5
  • figure 3
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Mast cells play a potentially important role in fibroproliferative diseases, releasing mediators including tryptase that are… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Tryptase is a serine protease secreted by mast cells that is able to activate other cells. In the present studies we have tested… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
The presence of mast cells near capillary sprouting sites suggests an association between mast cells and angiogenesis. However… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Proteinase-activated receptor-2 (PAR-2) is a G protein-coupled receptor that is cleaved and activated by trypsin-like enzymes… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
1991
Highly Cited
1991
Mast cells appear to promote fibroblast proliferation, presumably through secretion of growth factors, although the molecular… (More)
  • figure 1
  • table I
  • figure 3
  • table II
  • figure 5
Is this relevant?
Highly Cited
1989
Highly Cited
1989
Tryptase, a neutral protease of human mast cells, is a potentially important indicator of mast cell involvement in various… (More)
  • figure 2
  • figure 3
  • table I
  • figure 4
Is this relevant?
Highly Cited
1987
Highly Cited
1987
Better methods are needed to assess mast-cell activation in vivo and to distinguish the activation of mast cells from that of… (More)
Is this relevant?
Highly Cited
1981
Highly Cited
1981
Tryptase, the predominant neutral protease in human mast cell secretory granules, was purified to homogeneity from dissociated… (More)
Is this relevant?