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TRYPTASE

Known as: lung tryptase, Tryptases [Chemical/Ingredient], EC 3.4.21.59 
A family of serine endoproteinases usually expressed in mast cell secretory granules. These enzymes cleave protein substrates after arginine or… 
National Institutes of Health

Related topics

Related topics

20 relations
In BloodPeptidase GeneProcess of secretionProteolysis

Narrower (6)

Mcpt8 protein, mouseTryptase Beta-2, humanalpha-Tryptasesbeta-Tryptases

Broader (1)

Serine Proteases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Specific immunoglobulin E for staphylococcal enterotoxins in nasal polyps from patients with aspirin‐intolerant asthma
Background Nasal polyps infiltrated with eosinophils are commonly found in chronic asthmatic patients, more frequently in those… 
Review
2002
Review
2002
New developments in the genetics and activation of mast cell proteases.
Highly Cited
1999
Highly Cited
1999
Grass pollen immunotherapy decreases the number of mast cells in the skin
Allergen injection immunotherapy is effective for summer hay fever and reduces cutaneous sensitivity to grass pollen. 
Highly Cited
1997
Highly Cited
1997
The Three-dimensional Structure of Recombinant Leech-derived Tryptase Inhibitor in Complex with Trypsin
The x-ray crystal structure of recombinant leech-derived tryptase inhibitor (rLDTI) has been solved to a resolution of 1.9 Å in… 
Highly Cited
1991
Highly Cited
1991
Mast cell numbers and staining characteristics in the normal and allergic human conjunctiva.
Highly Cited
1990
Highly Cited
1990
The protease inhibitory properties of the Alzheimer's beta-amyloid precursor protein.
Highly Cited
1985
Highly Cited
1985
The fibrinogenolytic activity of purified tryptase from human lung mast cells.
The capacity of purified tryptase from human lung mast cells to metabolize human fibrinogen, fibrin, and plasminogen was… 
Highly Cited
1985
Highly Cited
1985
Chymotrypsin- and trypsin-type serine proteases in rat mast cells: properties and functions.
Highly Cited
1983
Highly Cited
1983
Generation of C3a anaphylatoxin from human C3 by human mast cell tryptase.
Tryptase, the dominant neutral protease of human pulmonary mast cell secretory granules, has the capacity in vitro to generate… 
Highly Cited
1983
Highly Cited
1983
Inactivation of human high molecular weight kininogen by human mast cell tryptase.
Tryptase, the major neutral protease of human pulmonary mast cell secretory granules, rapidly inactivates human high m.w… 
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