Peptidase Gene

Known as: Protease Gene, Proteinase Gene 
A gene that encodes an enzyme that is capable of hydrolyzing the peptide bonds found between amino acids in proteins.
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Selected missense mutations in the proprotein convertase subtilisin/kexin type 9 serine protease gene (PCSK9) cause autosomal… (More)
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Highly Cited
2005
Highly Cited
2005
Compounds A-782759 (an N-1-aza-4-hydroxyquinolone benzothiadiazine) and BILN-2061 are specific anti-hepatitis C virus (HCV… (More)
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Highly Cited
2004
Highly Cited
2004
BILN 2061 is a novel, specific hepatitis C virus (HCV) NS3 serine protease inhibitor discovered by Boehringer Ingelheim that has… (More)
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Highly Cited
2001
Highly Cited
2001
G-to-A hypermutation has been sporadically observed in human immunodeficiency virus type 1 (HIV-1) proviral sequences from… (More)
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Highly Cited
2000
Highly Cited
2000
Most human immunodeficiency virus (HIV) drug susceptibility studies have involved subtype B strains. Little information on the… (More)
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Highly Cited
1999
Highly Cited
1999
CONTEXT There is concern that the widespread use of antiretroviral drugs to treat human immunodeficiency virus 1 (HIV-1… (More)
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Highly Cited
1999
Highly Cited
1999
Combination antiretroviral therapy for HIV-1 infection has resulted in profound control of HIV replication in vivo, improved… (More)
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1999
1999
OBJECTIVE To assess the patterns of HIV phenotypic cross-resistance to protease inhibitors (PI) in patients experiencing viral… (More)
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Highly Cited
1998
Highly Cited
1998
Recent studies have shown that HIV-1 replication can be dramatically curtailed, if not completely arrested, with potent… (More)
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Highly Cited
1997
Highly Cited
1997
Two different responses to the therapy were observed in a group of patients receiving the protease inhibitor indinavir. In one… (More)
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