ADAM17 protein, human

Known as: TNF-Alpha-Converting Enzyme, TNF-Alpha Convertase, Antigen CD156b 
Disintegrin and metalloproteinase domain-containing protein 17 (824aa, ~93 kDa) is encoded by the human ADAM17 gene. This protein is involved in… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1958-2017
0204019582017

Papers overview

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2011
2011
Tumor necrosis factor-α–converting enzyme (TACE; also known as ADAM17) is a proteolytic sheddase that is responsible for the… (More)
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2005
Highly Cited
2005
Mucus hypersecretion is a prominent manifestation in patients with chronic inflammatory airway diseases and contributes to their… (More)
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2005
Highly Cited
2005
Tumor necrosis factor alpha-converting enzyme (TACE/ADAM17) has been implicated in the inducible shedding of numerous cell… (More)
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2004
Highly Cited
2004
Epidermal growth factor (EGF) family ligands are derived by proteolytic cleavage of the ectodomains of integral membrane… (More)
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2003
Highly Cited
2003
Communication between G protein-coupled receptor (GPCR) and epidermal growth factor receptor (EGFR) signalling systems involves… (More)
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2003
Highly Cited
2003
The factors and mechanisms that transduce the intracellular signals sent upon activation of the receptor for the epidermal growth… (More)
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2003
Highly Cited
2003
A variety of cell surface adhesion molecules can exist as both transmembrane proteins and soluble circulating forms. Increases in… (More)
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2002
Highly Cited
2002
We previously implicated tumor necrosis factor-alpha converting enzyme (TACE/ADAM17) in the processing of the integral membrane… (More)
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2000
Highly Cited
2000
The Notch1 receptor is presented at the cell membrane as a heterodimer after constitutive processing by a furin-like convertase… (More)
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1998
Highly Cited
1998
TNF-alpha converting enzyme (TACE; ADAM-17) is a membrane-bound disintegrin metalloproteinase that processes the membrane… (More)
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