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ADAM15 protein, human

Known as: Disintegrin and Metalloproteinase Domain-Containing Protein 15, MDC-15, Metalloprotease RGD Disintegrin Protein 
Disintegrin and metalloproteinase domain-containing protein 15 (863 aa, ~93 kDa) is encoded by the human ADAM15 gene. This protein is involved in… 
National Institutes of Health

Related topics

Related topics

14 relations

Broader (2)

ADAM ProteinsMembrane Proteins
ADAM15 geneCell AdhesionDisintegrin DomainEnzyme Gene

Papers overview

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Highly Cited
2010
Highly Cited
2010
ADAM15 regulates endothelial permeability and neutrophil migration via Src/ERK1/2 signalling.
AIMS Endothelial barrier dysfunction is a key event in the pathogenesis of vascular diseases associated with inflammation. ADAM… 
Highly Cited
2009
Highly Cited
2009
Genetic inactivation of ADAMTS15 metalloprotease in human colorectal cancer.
Matrix metalloproteinases have been traditionally linked to cancer dissemination through their ability to degrade most… 
Highly Cited
2002
Highly Cited
2002
Phosphorylation-dependent Interactions between ADAM15 Cytoplasmic Domain and Src Family Protein-tyrosine Kinases*
The adamalysins (ADAMs) are transmembrane glycoproteins involved in cell adhesion and proteolytic ectodomain processing of… 
Review
1999
Review
1999
Metalloprotease-disintegrins: modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding.
Metalloprotease-disintegrins (ADAMs) have captured our attention as key players in fertilization and in the processing of the… 
Highly Cited
1999
Highly Cited
1999
Interaction of metargidin (ADAM-15) with alphavbeta3 and alpha5beta1 integrins on different haemopoietic cells.
Metargidin (ADAM-15) is a type I transmembrane glycoprotein belonging to the ADAM (A Disintegrin and Metalloprotease Domain… 
Highly Cited
1999
Highly Cited
1999
Interaction of the Metalloprotease Disintegrins MDC9 and MDC15 with Two SH3 Domain-containing Proteins, Endophilin I and SH3PX1*
Metalloprotease disintegrins (a disintegrin and metalloprotease (ADAM) and metalloprotease, disintegrin,cysteine-rich proteins… 
Highly Cited
1998
Highly Cited
1998
Intracellular Maturation of the Mouse Metalloprotease Disintegrin MDC15*
Metalloprotease disintegrins are a family of membrane-anchored glycoproteins that play a role in fertilization, myoblast fusion… 
Highly Cited
1997
Highly Cited
1997
Expression of members of the novel membrane linked metalloproteinase family ADAM in cells derived from a range of haematological malignancies.
ADAMs (A disintegrin and metalloproteinase) are a recently discovered family of proteins with significant primary sequence… 
Highly Cited
1996
Highly Cited
1996
Metargidin, a Membrane-anchored Metalloprotease-Disintegrin Protein with an RGD Integrin Binding Sequence (*)
Cellular disintegrins are a family of membrane-anchored proteins with structural homology to snake venom metalloproteases and… 
Highly Cited
1992
Highly Cited
1992
Effect of thrombin treatment of tumor cells on adhesion of tumor cells to platelets in vitro and tumor metastasis in vivo.
Seven different tumor cell lines (human melanoma SK MEL 28; hamster melanoma HM29; murine melanomas B16F10 and amelanotic… 
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