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Tryptase Beta-2, human

Known as: Tryptase Beta-2, Tryptase Beta III, Tryptase II 
Tryptase beta-2 (275 aa, ~31 kDa) is encoded by the human TPSB2 gene. This protein is involved in protein degradation.
National Institutes of Health

Related topics

Related topics

12 relations
ChymaseEnzyme GeneExtracellular SpaceHydrolysis

Broader (1)

TRYPTASE

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Identification of 6-substituted 4-arylsulfonyl-1,4-diazepane-2,5-diones as a novel scaffold for human chymase inhibitors.
2004
2004
The genes encoding NK cell granule serine proteases, human tryptase-2 (TRYP2) and human granzyme A (HFSP), both map to chromosome 5q11-q12 and define a new locus for cytotoxic lymphocyte granule…
This submission in the Gene Antigen Register section of Immunogenetics journal describes research in which fluorescence in situ… 
Highly Cited
2003
Highly Cited
2003
Albumin Is a Substrate of Human Chymase
Human chymase is a chymotryptic serine peptidase stored and secreted by mast cells. Compared with other chymotryptic enzymes… 
2003
2003
Structure of human pro-chymase: a model for the activating transition of granule-associated proteases.
Human chymase is a protease involved in physiological processes ranging from inflammation to hypertension. As are all proteases… 
Highly Cited
2002
Highly Cited
2002
Mast Cell Chymase Degrades ApoE and ApoA-II in ApoA-I–Knockout Mouse Plasma and Reduces Its Ability to Promote Cellular Cholesterol Efflux
Objective—Mast cell chymase is a chymotryptic heparin proteoglycan–bound neutral protease that exerts its activity in… 
1998
1998
Human Chymase, an Enzyme Forming Novel Bioactive 31-Amino Acid Length Endothelins
We report the novel role of human chymase in the production of bioactive 31-amino acid length endothelins (ETs), which may play a… 
1997
1997
Production of crystallizable human chymase from a Bacillus subtilis system
Highly Cited
1996
Highly Cited
1996
Mast cells expressing chymase but not tryptase can be derived by culturing human progenitors in conditioned medium obtained from a human mastocytosis cell strain with c-kit ligand.
Human mast cells (MC) were derived from umbilical cord blood and bone marrow progenitors cultured in the presence of a… 
1993
1993
Dipeptide processing activates recombinant human prochymase.
Human chymase (h-chymase) is a serine protease that efficiently converts angiotensin I to II. Its structure and homology to other… 
Highly Cited
1989
Highly Cited
1989
Reaction of human skin chymotrypsin-like proteinase chymase with plasma proteinase inhibitors.
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