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Chymase

Known as: Chymases [Chemical/Ingredient], Chymotrypsin Like Proteases, Chymotrypsin Like Protease 
A family of neutral serine proteases with CHYMOTRYPSIN-like activity. Chymases are primarily found in the SECRETORY GRANULES of MAST CELLS and are… 
National Institutes of Health

Related topics

Related topics

24 relations
CMA1 geneCTRL geneEnzyme GeneExtracellular Matrix Degradation

Narrower (2)

Cma1 protein, mousechymase 2

Broader (1)

Serine Proteases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2020
Highly Cited
2020
Identification of chymotrypsin-like protease inhibitors of SARS-CoV-2 via integrated computational approach
Abstract Recently, the world has witnessed outbreak of a novel Coronavirus (SARS-CoV-2), the virus which initially emerged in… 
Review
2002
Review
2002
Ophidian envenomation strategies and the role of purines.
Review
1997
Review
1997
Development, significance, and heterogeneity of mast cells with particular regard to the mast cell‐specific proteases chymase and tryptase
Mast cells are one of the major effector cells in the pathogenesis of the immediate‐type hypersensitivity reaction in a number of… 
Review
1997
Review
1997
Evolutionary Divergence of Substrate Specificity within the Chymotrypsin-like Serine Protease Fold*
One of the enduring paradigms in enzymology is the theme of evolutionary divergence in substrate specificity from a parental… 
Highly Cited
1993
Highly Cited
1993
Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB
INDUCIBLE gene expression in eukaryotes is mainly controlled by the activity of transcriptional activator proteins, such as NF-κB… 
Highly Cited
1993
Highly Cited
1993
Cellular localization and regional distribution of an angiotensin II-forming chymase in the heart.
The human heart is a target organ for the octapeptide hormone, angiotensin II (Ang II). Recent studies suggest that the human… 
Highly Cited
1989
Highly Cited
1989
Detection of MCT and MCTC types of human mast cells by immunohistochemistry using new monoclonal anti-tryptase and anti-chymase antibodies.
We developed an improved immunohistochemical technique for distinguishing human mast cells of the MCT (tryptase-positive, chymase… 
Review
1989
Review
1989
Cysteine proteases of positive strand RNA viruses and chymotrypsin‐like serine proteases
Highly Cited
1988
Highly Cited
1988
Unfolding free energy changes determined by the linear extrapolation method. 2. Incorporation of delta G degrees N-U values in a thermodynamic cycle.
The linear extrapolation method was used to evaluate the unfolding free energy changes (delta G degrees N-U) for… 
Review
1981
Review
1981
Assay of coagulation proteases using peptide chromogenic and fluorogenic substrates.
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