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Chymase
Known as:
Chymases [Chemical/Ingredient]
, Chymotrypsin Like Proteases
, Chymotrypsin Like Protease
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A family of neutral serine proteases with CHYMOTRYPSIN-like activity. Chymases are primarily found in the SECRETORY GRANULES of MAST CELLS and are…
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National Institutes of Health
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Related topics
Related topics
24 relations
CMA1 gene
CTRL gene
Enzyme Gene
Extracellular Matrix Degradation
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Narrower (2)
Cma1 protein, mouse
chymase 2
Broader (1)
Serine Proteases
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2007
Review
2007
Mast cell tryptases and chymases in inflammation and host defense
G. Caughey
Immunological Reviews
2007
Corpus ID: 23245423
Summary: Tryptases and chymases are the major proteins stored and secreted by mast cells. The types, amounts, and properties of…
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Review
2006
Review
2006
Nidovirales: Evolving the largest RNA virus genome
A. Gorbalenya
,
L. Enjuanes
,
J. Ziebuhr
,
E. Snijder
Virus Research
2006
Corpus ID: 23704652
Review
2006
Review
2006
The role of the mast cell in the pathophysiology of asthma.
P. Bradding
,
A. Walls
,
S. Holgate
Journal of Allergy and Clinical Immunology
2006
Corpus ID: 25506059
Highly Cited
2005
Highly Cited
2005
A Key Role for Mast Cell Chymase in the Activation of Pro-matrix Metalloprotease-9 and Pro-matrix Metalloprotease-2*
Elena Tchougounova
,
A. Lundequist
,
I. Fajardo
,
J. Winberg
,
M. Åbrink
,
G. Pejler
Journal of Biological Chemistry
2005
Corpus ID: 25081099
Chymases, serine proteases exclusively expressed by mast cells, have been implicated in various pathological conditions. However…
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Review
1997
Review
1997
Development, significance, and heterogeneity of mast cells with particular regard to the mast cell‐specific proteases chymase and tryptase
M. Welle
Journal of Leukocyte Biology
1997
Corpus ID: 22579597
Mast cells are one of the major effector cells in the pathogenesis of the immediate‐type hypersensitivity reaction in a number of…
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Highly Cited
1994
Highly Cited
1994
Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments
Jianyi Ma
,
A. Yee
,
H. Brewer
,
Saumya Das
,
H. Potter
Nature
1994
Corpus ID: 4229989
THE protease inhibitor α,-antichymotrypsin and the lipid transport protein apolipoprotein E (apoE) are intimately associated with…
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Highly Cited
1993
Highly Cited
1993
Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB
T. Henkel
,
T. Machleidt
,
I. Alkalay
,
M. Krönke
,
Y. Ben-Neriah
,
P. Baeuerle
Nature
1993
Corpus ID: 4253275
INDUCIBLE gene expression in eukaryotes is mainly controlled by the activity of transcriptional activator proteins, such as NF-κB…
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Highly Cited
1989
Highly Cited
1989
Detection of MCT and MCTC types of human mast cells by immunohistochemistry using new monoclonal anti-tryptase and anti-chymase antibodies.
A. Irani
,
T. Bradford
,
C. Kepley
,
N. Schechter
,
L. Schwartz
Journal of Histochemistry and Cytochemistry
1989
Corpus ID: 82691
We developed an improved immunohistochemical technique for distinguishing human mast cells of the MCT (tryptase-positive, chymase…
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Highly Cited
1988
Highly Cited
1988
Unfolding free energy changes determined by the linear extrapolation method. 1. Unfolding of phenylmethanesulfonyl alpha-chymotrypsin using different denaturants.
M. Santoro
,
D. W. Bolen
Biochemistry
1988
Corpus ID: 24319805
Characteristics and properties of the unfolding free energy change, delta G degrees N-U, as determined by the linear…
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Highly Cited
1987
Highly Cited
1987
Quantitation of histamine, tryptase, and chymase in dispersed human T and TC mast cells.
L. Schwartz
,
A. Irani
,
K. Roller
,
M. Castells
,
N. Schechter
Journal of Immunology
1987
Corpus ID: 44371973
Levels of histamine, chymase, and tryptase were assessed in preparations of dispersed human TC (tryptase+, chymase+) mast cells…
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