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TNFSF13B protein, human

Known as: Dendritic Cell-Derived TNF-Like Molecule, Antigen CD257, CD257 Antigen 
Tumor necrosis factor ligand superfamily member 13B (285 aa, ~31 kDa) is encoded by the human TNFSF13B gene. This protein is involved in signal… 
National Institutes of Health

Related topics

Related topics

17 relations
Apoptosis Regulatory ProteinsB-Cell Activating Factor MeasurementB-Cell Immune Response PathwayCell Death

Broader (1)

TALL-1 protein

Papers overview

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Highly Cited
2009
Highly Cited
2009
Altered B-cell homeostasis and excess BAFF in human chronic graft-versus-host disease.
Chronic graft-versus-host disease (cGVHD) causes significant morbidity and mortality in patients otherwise cured of malignancy… 
Review
2007
Review
2007
Astrocytes are active players in cerebral innate immunity.
Review
2007
Review
2007
B cells and the BAFF/APRIL axis: fast-forward on autoimmunity and signaling.
Highly Cited
2006
Highly Cited
2006
Similarities and differences between selective and nonselective BAFF blockade in murine SLE.
B cells have multiple roles in immune activation and inflammation separate from their capacity to produce antibodies. B cell… 
Highly Cited
2006
Highly Cited
2006
BAFF controls B cell metabolic fitness through a PKCβ- and Akt-dependent mechanism
B cell life depends critically on the cytokine B cell–activating factor of the tumor necrosis factor family (BAFF). Lack of BAFF… 
Highly Cited
2005
Highly Cited
2005
The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature.
B-cell activating factor (BAFF) and a proliferation-inducing ligand (APRIL) have been shown to promote multiple myeloma (MM) cell… 
Highly Cited
2004
Highly Cited
2004
B Cell-Activating Factor Belonging to the TNF Family Acts through Separate Receptors to Support B Cell Survival and T Cell-Independent Antibody Formation
The TNF-related ligand, B cell-activating factor belonging to the TNF family (BAFF), is necessary for normal B cell development… 
Highly Cited
2003
Highly Cited
2003
Normal Induction but Attenuated Progression of Germinal Center Responses in BAFF and BAFF-R Signaling–Deficient Mice
The factors regulating germinal center (GC) B cell fate are poorly understood. Recent studies have defined a crucial role for the… 
Highly Cited
2002
Highly Cited
2002
BLyS and APRIL Form Biologically Active Heterotrimers That Are Expressed in Patients with Systemic Immune-Based Rheumatic Diseases1
BLyS and APRIL are two members of the TNF superfamily that are secreted by activated myeloid cells and have costimulatory… 
Highly Cited
2000
Highly Cited
2000
Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity
B ymphocyte stimulator (BLyS) is a member of the tumor necrosis factor (TNF) superfamily. BLyS stimulates proliferation of, and… 
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