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TLR8 gene

Known as: Toll-Like Receptor 8 Gene, TLR8, CD288 
This gene plays a role in receptor signaling and in immune responses.
National Institutes of Health

Related topics

Related topics

6 relations
Immune responseLigand BindingReceptor SignalingTLR8 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Abstract 3264: A novel TLR8 agonist induces immune responses and tumor regression
Toll like receptors (TLRs) have been a recent focus of drug discovery for cancer immunotherapy. TLRs play a crucial role in… 
2017
2017
Sustained efficacy and surface antigen seroconversion in the woodchuck model of chronic hepatitis B with the selective toll-like receptor 8 agonist GS-9688
2017
2017
In vitro and in vivo characterization of the selective toll-like receptor 8 agonist GS-9688
2016
2016
Identification and characterization of the toll-like receptor 8 gene in the Chinese raccoon dog (Nyctereutes procyonoides).
2016
2016
Motolimod effectively drives immune activation in advanced cancer patients
ABSTRACT A novel approach to immunotherapy is the activation of toll-like receptor 8 (TLR8). Motolimod, a selective TLR8 agonist… 
2015
2015
Enrichment Assessment of Multiple Virtual Screening Strategies for Toll‐Like Receptor 8 Agonists Based on a Maximal Unbiased Benchmarking Data Set
Toll‐like receptor 8 agonists, which activate adaptive immune responses by inducing robust production of T‐helper 1‐polarizing… 
2015
2015
Molecular cloning and functional characterization of murine toll-like receptor 8
Toll-like receptors (TLRs) are a large family of germ-line encoded pattern recognition receptors (PRRs) that recognize pathogen… 
2009
2009
Polymorphisms of TLR7 and TLR8 associated with risk of asthma and asthma-related phenotypes in a southeastern Chinese Han population
2009
2009
Modulation of TOLL-like receptor 3 expression by antisense oligonucleotides
Antisense oligonucleotide compounds, compositions and methods are provided for down regulating the expression of TLR3. The… 
2004
2004
Immunostimulant composition comprising at least one toll-like receptor 7 or toll-like receptor 8 agonist and a toll-like receptor 4 agonist
The invention relates to an immunostimulant composition comprising at least one Toll-like receptor 7 or Toll-like receptor 8… 
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