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TLR8 gene
Known as:
Toll-Like Receptor 8 Gene
, TLR8
, CD288
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This gene plays a role in receptor signaling and in immune responses.
National Institutes of Health
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Related topics
Related topics
6 relations
Immune response
Ligand Binding
Receptor Signaling
TLR8 protein, human
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Characterization, evolution, and expression analysis of TLR7 gene subfamily members in Mastacembelus armatus (Synbranchiformes: Mastacembelidae)
Chong Han
,
Qiang Li
,
Jinmei Liu
,
Zhiqiang Hao
,
Jianrong Huang
,
Yong Zhang
Developmental and Comparative Immunology
2019
Corpus ID: 73420623
2017
2017
A phase 2, randomized, double-blind, placebo- controlled study of chemo-immunotherapy combination using motolimod with pegylated liposomal doxorubicin in recurrent or persistent ovarian cancer: a…
B. Monk
,
M. Brady
,
+20 authors
G. Coukos
Annals of Oncology
2017
Corpus ID: 2720878
Background A phase 2, randomized, placebo-controlled trial was conducted in women with recurrent epithelial ovarian carcinoma to…
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2015
2015
Enrichment Assessment of Multiple Virtual Screening Strategies for Toll‐Like Receptor 8 Agonists Based on a Maximal Unbiased Benchmarking Data Set
Fen Pei
,
Hongwei Jin
,
+4 authors
L. Zhang
Chemical Biology and Drug Design
2015
Corpus ID: 34900430
Toll‐like receptor 8 agonists, which activate adaptive immune responses by inducing robust production of T‐helper 1‐polarizing…
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Highly Cited
2014
Highly Cited
2014
Estrogen modulation of endosome-associated toll-like receptor 8: an IFNα-independent mechanism of sex-bias in systemic lupus erythematosus.
N. Young
,
Lai-Chu Wu
,
+7 authors
W. Jarjour
Clinical Immunology
2014
Corpus ID: 45939372
Highly Cited
2014
Highly Cited
2014
Endosomal Localization of TLR8 Confers Distinctive Proteolytic Processing on Human Myeloid Cells
N. Ishii
,
Kenji Funami
,
Megumi Tatematsu
,
T. Seya
,
M. Matsumoto
Journal of Immunology
2014
Corpus ID: 21626174
Nucleic acid–sensing TLRs are involved in both antimicrobial immune responses and autoimmune inflammation. TLR8 is…
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Highly Cited
2011
Highly Cited
2011
TLR7 and TLR8 Gene Variations and Susceptibility to Hepatitis C Virus Infection
Chiou-Huey Wang
,
H. Eng
,
+4 authors
Tsun-Mei Lin
PLoS ONE
2011
Corpus ID: 15573337
Toll-like receptors (TLRs) play pivotal roles in the innate immune system and control inflammatory responses and adaptive…
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Highly Cited
2008
Highly Cited
2008
A functional toll-like receptor 8 variant is associated with HIV disease restriction.
D. Oh
,
S. Taube
,
+13 authors
R. Schumann
Journal of Infectious Diseases
2008
Corpus ID: 22598399
BACKGROUND Toll-like receptors (TLRs) play an important role in the innate immune response to pathogens. TLR8 has been found to…
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2008
2008
Innate immune response gene expression profiles characterize primary antiphospholipid syndrome
I. Bernales
,
A. Fullaondo
,
+4 authors
A. Zubiaga
Genes and Immunity
2008
Corpus ID: 9154341
Primary antiphospholipid syndrome (PAPS) is a systemic autoimmune disorder characterized by thromboembolic episodes and pregnant…
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2008
2008
Association between toll-like receptor 8 expression and adverse clinical outcomes in patients with enterovirus-associated dilated cardiomyopathy.
M. Satoh
,
T. Akatsu
,
Y. Ishikawa
,
Y. Minami
,
Yuji Takahashi
,
Motoyuki Nakamura
American Heart Journal
2008
Corpus ID: 20732272
Highly Cited
2007
Highly Cited
2007
Administration of a dual toll-like receptor 7 and toll-like receptor 8 agonist protects against influenza in rats.
D. Hammerbeck
,
G. Burleson
,
+6 authors
Richard L. Miller
Antiviral Research
2007
Corpus ID: 8035142
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