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TAP1 protein, human

Known as: Peptide Supply Factor 1, ATP-Binding Cassette Sub-Family B Member 2, ABCB2 protein, human 
Antigen peptide transporter 1 (808 aa, ~87 kDa) is encoded by the human TAP1 gene. This protein plays a role in cytoplasmic antigen transport and… 
National Institutes of Health

Related topics

Related topics

30 relations
Adenosine TriphosphatasesAntigen Presentation PathwayAntigen ProcessingAntigen-Presenting Cells

Broader (1)

Antigen Peptide Transporter-1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Viral degradation of the MHC class I peptide loading complex.
Highly Cited
2003
Highly Cited
2003
MHC class I‐deficient metastatic tumor variants immunoselected by T lymphocytes originate from the coordinated downregulation of APM components
Previous reports from our group indicated that the MHC class I phenotype of metastatic lung colonies produced by a mouse… 
Highly Cited
2001
Highly Cited
2001
Enhanced expression of human ABC‐transporter tap is associated with cellular resistance to mitoxantrone
Highly Cited
2000
Highly Cited
2000
Transcriptional regulation of the major histocompatibility complex (MHC) class I heavy chain, TAP1 and LMP2 genes by the human papillomavirus (HPV) type 6b, 16 and 18 E7 oncoproteins
We have examined the possibility that the E7 proteins of the high-risk human papillomavirus (HPV) type 16 and 18 and the… 
Highly Cited
1999
Highly Cited
1999
Lateral diffusion of GFP-tagged H2Ld molecules and of GFP-TAP1 reports on the assembly and retention of these molecules in the endoplasmic reticulum.
Highly Cited
1998
Highly Cited
1998
Different Requirements for Signal Transducer and Activator of Transcription 1α and Interferon Regulatory Factor 1 in the Regulation of Low Molecular Mass Polypeptide 2 and Transporter Associated with…
The components of the antigen processing machinery, low molecular mass polypeptide (LMP) 2 and transporter associated with… 
Highly Cited
1995
Highly Cited
1995
Assembly, Intracellular Localization, and Nucleotide Binding Properties of the Human Peptide Transporters TAP1 and TAP2 Expressed by Recombinant Vaccinia Viruses (*)
The transporter associated with antigen processing (TAP) transports short peptides from the cytosol to the endoplasmic reticulum… 
Highly Cited
1994
Highly Cited
1994
Interaction of MHC class I molecules with the transporter associated with antigen processing.
The transporter associated with antigen processing (TAP) delivers cytosolic peptides into the endoplasmic reticulum (ER) where… 
Highly Cited
1994
Highly Cited
1994
TAP (transporter associated with antigen processing)-independent presentation of endogenously synthesized peptides is enhanced by endoplasmic reticulum insertion sequences located at the amino- but…
Under most circumstances, cell surface MHC class I molecules display peptides derived from a cytosolic pool of proteins. The… 
Highly Cited
1993
Highly Cited
1993
TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective
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