Syk kinase

Known as: Syk Kinase [Chemical/Ingredient], SYK Tyrosine Kinase, Spleen Tyrosine Kinase 
An SH2 domain-containing non-receptor tyrosine kinase that regulates signal transduction downstream of a variety of receptors including B-CELL… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2017
0102019932017

Papers overview

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Highly Cited
2009
Highly Cited
2009
Oxidative modification of low-density lipoprotein (LDL) plays a causative role in the development of atherosclerosis. In this… (More)
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2007
2007
Curcumin (diferuloylmethane), a component of dietary spice turmeric (Curcuma longa), has been shown in recent studies to have… (More)
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2006
2006
Leukocyte adhesion via 2 integrins (CD11/CD18) activates the tyrosine kinase Syk. We found that Syk was enriched at the… (More)
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2006
2006
The protein tyrosine kinase Syk plays a central role in Fcgamma receptor-mediated phagocytosis in the adaptive immune system. We… (More)
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2004
2004
BACKGROUND Ongoing secretion from human basophils is a balance of activation and deactivation events. Recent studies have focused… (More)
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2001
2001
While beta 2 integrin ligand-receptor recognition interactions are well characterized, less is known about how these events… (More)
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1999
1999
Lymphocytes accumulate within the extracellular matrix (ECM) of tumor, wound, or inflammatory tissues. These tissues are largely… (More)
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Highly Cited
1997
Highly Cited
1997
Activation of the syk tyrosine kinase occurs almost immediately following engagement of many types of antigen receptors… (More)
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1996
1996
Ligation of CD38 inhibits proliferation and induces apoptosis of human immature B cells, but the molecular mechanisms underlying… (More)
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1995
1995
The IL-2 receptor (IL-2R) consists of three subunits, the IL-2R alpha, IL-2R beta, and IL-2R gamma chains. The IL-2-induced… (More)
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