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Substance P

Known as: Euler Gaddum Substance P, neurokinin 1, Substance P, Euler-Gaddum 
An eleven-amino acid neurotransmitter that appears in both the central and peripheral nervous systems. It is involved in transmission of PAIN, causes… 
National Institutes of Health

Related topics

Related topics

37 relations

Narrower (20)

Bolton Hunter reagent-substance P conjugateGR 71251GR 73632Hypothalamic Substance P
In BloodProcess of secretionSubstance P ReceptorSubstance P:MCnc:Pt:CSF:Qn

Broader (5)

NeuroregulatorsNeurotransmitter AgentsNeurotransmittersPeptides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1991
Highly Cited
1991
Neurokinin and NMDA antagonists (but not a kainic acid antagonist) are antinociceptive in the mouse formalin model
Highly Cited
1989
Highly Cited
1989
The effects of intrathecal galanin and C-fiber stimulation on the flexor reflex in the rat
Highly Cited
1987
Highly Cited
1987
Characterization of neurokinin receptors in various isolated organs by the use of selective agonists.
Highly Cited
1987
Highly Cited
1987
Relative potencies of neurokinins in guinea pig trachea and human bronchus.
Highly Cited
1986
Highly Cited
1986
Substance P: binding properties and studies on cellular responses in guinea pig macrophages.
The neuropeptide Substance P (SP) has been recognized to modulate functional activities of inflammatory cells. We have previously… 
Highly Cited
1984
Highly Cited
1984
Origins of peptide and norepinephrine nerves in the mucosa of the guinea pig small intestine.
Highly Cited
1981
Highly Cited
1981
Biochemical and anatomical observations on the degeneration of peptide-containing primary afferent neurons after neonatal capsaicin
Highly Cited
1981
Highly Cited
1981
A specific substance P antagonist blocks smooth muscle contractions induced by non-cholinergic, non-adrenergic nerve stimulation
Nerve fibres containing substance P (SP) are widely distributed in the body1–3 and seem to innervate autonomic ganglia, blood… 
Highly Cited
1981
Highly Cited
1981
Inhibition of antidromic and substance P-induced vasodilatation by a substance P antagonist.
Indirect evidence has abundantly been presented to support the view that substance P (SP) is involved in the vasodilatation… 
Highly Cited
1979
Highly Cited
1979
In vivo and in vitro effects of substance P and neurotensin on gonadotropin and prolactin release.
Conscious ovariectomized rats bearing a cannula implanted in the third ventricle were injected with 2 μl 0.9% NaCl containing… 
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