• Publications
  • Influence
Brain-Derived Neurotrophic Factor Induces Long-Term Potentiation in Intact Adult Hippocampus: Requirement for ERK Activation Coupled to CREB and Upregulation of Arc Synthesis
Brain-derived neurotrophic factor (BDNF) is implicated in long-term synaptic plasticity in the adult hippocampus, but the cellular mechanisms are little understood. Here we used intrahippocampalExpand
  • 696
  • 65
  • PDF
Induction of c-fos-like protein in spinal cord neurons following sensory stimulation
It has been suggested that the proto-oncogenes c-fos and c-myc participate in the control of genetic events which lead to the establishment of prolonged functional changes in neurons1,2. ExpressionExpand
  • 1,912
  • 56
Superficial NK1-expressing neurons control spinal excitability through activation of descending pathways
The increase in pain sensitivity that follows injury is regulated by superficially located projection neurons in the dorsal horn of the spinal cord that express the neurokinin-1 (NK1) receptor. AfterExpand
  • 409
  • 42
The molecular dynamics of pain control
Pain is necessary for survival, but persistent pain can result in anxiety, depression and a reduction in the quality of life. The discriminative and affective qualities of pain are both thought to beExpand
  • 560
  • 30
Differential expression of immediate early genes in the hippocampus and spinal cord
We have demonstrated that immediate early genes can be differentially activated within the central nervous system. We examined the effects of tetanic stimulation in the hippocampus and of noxiousExpand
  • 663
  • 25
Projections of the nucleus of the basal optic root in the pigeon: An autoradiographic and horseradish peroxidase study
The efferent projections of the nBOR complex, have been studied with both anterograde autoradiographic and retrograde horseradish peroxidase (HRP) techniques. The nBOR complex includes three distinctExpand
  • 199
  • 24
Amphiphysin heterodimers: potential role in clathrin-mediated endocytosis.
Amphiphysin (Amph) is a src homology 3 domain-containing protein that has been implicated in synaptic vesicle endocytosis as a result of its interaction with dynamin. In a screen for novel members ofExpand
  • 252
  • 23
  • PDF
Light pulses that shift rhythms induce gene expression in the suprachiasmatic nucleus.
Lighting cycles synchronize (entrain) mammalian circadian rhythms by altering activity of cells in the suprachiasmatic nucleus (SCN) of the hypothalamus, a circadian pacemaker. Exposure of hamstersExpand
  • 541
  • 22
Observations on the projections and intrinsic organization of the pigeon optic tectum: An autoradiographic study based on anterograde and retrograde, axonal and dendritic flow
  • S. Hunt, H. Künzle
  • Biology, Medicine
  • The Journal of comparative neurology
  • 15 November 1976
Three aspects of the labelling pattern seen after the injection of 13 different radioactive amino acids into the pigeon optic tectum have been described: The efferent projections of the optic tectum;Expand
  • 280
  • 17
Descending facilitatory control of mechanically evoked responses is enhanced in deep dorsal horn neurones following peripheral nerve injury
Pain resulting from peripheral nerve injury, characterised by ongoing pain, hyperalgesia and allodynia arises from peripheral and central processes. Here, we studied the potential role of centralExpand
  • 195
  • 13