Sterol Biosynthesis Pathway

Known as: Sterol Biosynthesis, sterol formation, sterol synthesis 
The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
p53 is a frequent target for mutation in human tumors, and mutant p53 proteins can actively contribute to tumorigenesis. We… (More)
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Highly Cited
2011
Highly Cited
2011
Little is known about the protective role of inflammatory processes in modulating lipid metabolism in infection. Here we report… (More)
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Highly Cited
2010
Highly Cited
2010
Huntington's disease (HD), an incurable neurodegenerative disorder, has a complex pathogenesis including protein aggregation and… (More)
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Highly Cited
2004
Highly Cited
2004
A crucial role for sterols in plant growth and development is underscored by the identification of three Arabidopsis sterol… (More)
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Highly Cited
2003
Highly Cited
2003
Sterol biosynthesis is viewed primarily as a eukaryotic process, and the frequency of its occurrence in bacteria has long been a… (More)
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Highly Cited
2001
Highly Cited
2001
Sterol levels affect the expression of many genes in yeast and humans. We found that the paralogous transcription factors Upc2p… (More)
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Highly Cited
2001
Highly Cited
2001
The mechanism by which human immunodeficiency virus (HIV) protease inhibitor therapy adversely induces lipodystrophy and… (More)
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Review
1997
Review
1997
Inhibitors of sterol and phospholipid biosynthesis in kinetoplastid parasites such as Trypanosoma cruzi, the causative agent of… (More)
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Highly Cited
1992
Highly Cited
1992
Some bisphosphonates used for the treatment of bone disorders are also potent inhibitors of squalene synthase, a critical enzyme… (More)
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Highly Cited
1983
Highly Cited
1983
This study was undertaken to measure and compare the rates at which digitonin-precipitable sterols (DPS) were synthesized in vivo… (More)
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