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Sterol Biosynthesis Pathway

Known as: Sterol Biosynthesis, sterol formation, sterol synthesis 
The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in… 
National Institutes of Health

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17-Beta-Hydroxysteroid Dehydrogenase 7HMGCR protein, humanHSD17B7 wt AlleleNAD(P)H dehydrogenase (quinone) 1, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1984
1984
Age-related decreases in tissue sterol acquisition are mediated by changes in cholesterol synthesis and not low density lipoprotein uptake in the rat.
The present investigation compared plasma cholesterol levels and lipoprotein profiles, and absolute rates of sterol synthesis and… 
Highly Cited
1980
Highly Cited
1980
Rapid regulation of the activity of the low density lipoprotein receptor of cultured human fibroblasts.
Regulation of low density lipoprotein (LDL) receptor activity of cultured human skin fibroblasts was studied by measuring 4… 
1980
1980
In vitro cholesterol synthesis in freshly isolated mononuclear cells of human blood: effect of in vivo administration of clofibrate and/or cholestyramine.
The rate of incorporation of [2-14C]acetate into cholesterol has been measured in freshly isolated peripheral blood mononuclear… 
1980
1980
Sterol metabolism and lymphocyte function: inhibition of endogenous sterol biosynthesis does not prevent mitogen-induced human T lymphocyte activation.
1979
1979
Regulation of cholesterol synthesis in primary rat hepatocyte culture cells. Possible regulatory site at sterol demethylation.
Primary rat hepatocyte culture cells were used to study the acute regulation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA… 
Highly Cited
1977
Highly Cited
1977
Mechanism of induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase in human leukocytes.
Incubation of leukocytes in buffer alone devoid of lipoproteins does not lead to the induction of 3-hydroxy-3-methylglutaryl… 
1977
1977
14alpha-ethyl-5alpha-cholest-7-ene-3beta,15alpha-diol, an extraodinarily potent inhibitor of sterol biosynthesis in animal cells.
Highly Cited
1975
Highly Cited
1975
Control of sterol synthesis and of hydroxymethylglutaryl CoA reductase in skin fibroblasts grown from patients with homozygous type II hyperlipoproteinemia.
In skin fibroblasts grown from four children with a homozygous form of type II hyperlipoproteinemia, the feedback control of… 
1967
1967
Phytosterol biosynthesis: evidence for a 24-ethylidene intermediate during sterol formation in Ochromonas malhamensis.
The 24-ethyl and 24-ethylidene groups present in various phytosterols arise by two successive trans-methylations from methionine… 
1962
1962
SOME FACTORS AFFECTING STEROL FORMATION IN SACCHAROMYCES CEREVISIAE
Starr, Patricia R. (Oregon State University, Corvallis) and L. W. Parks. Some factors affecting sterol formation in Saccharomyces… 
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