NAD(P)H dehydrogenase (quinone) 1, human

Known as: EC 1.6.5.2, Diaphorase-4, NQO1 
NAD(P)H dehydrogenase [quinone] 1 (274 aa, ~31 kDa) is encoded by the human NQO1 gene. This protein is involved in hydroquinone synthesis.
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
  • Ια, Ιγ, Ιβ
  • 2012
NADH:quinone oxidoreductase (complex I) pumps protons across the inner membrane of mitochondria or the plasma membrane of many… (More)
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Highly Cited
2006
Highly Cited
2006
DJ-1/PARK7, a cancer- and Parkinson's disease (PD)-associated protein, protects cells from toxic stresses. However, the… (More)
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Highly Cited
2005
Highly Cited
2005
The antioxidant response element (ARE) and Nrf2 are known to regulate the expression and coordinated induction of genes encoding… (More)
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Highly Cited
2004
Highly Cited
2004
Experiments using purified recombinant human NAD(P)H:quinone oxidoreductase 1 (NQO1) revealed that the auto-oxidation of fully… (More)
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Highly Cited
2001
Highly Cited
2001
Five hydrocarbon-oxidizing strains were isolated from formation waters of oilfields in Russia, Kazakhstan and China. These… (More)
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Highly Cited
2001
Highly Cited
2001
The tumor suppressor gene wild-type p53 encodes a labile protein that accumulates in cells after different stress signals and can… (More)
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Highly Cited
1997
Highly Cited
1997
alpha-Tocopherolquinone (TQ), a product of alpha-tocopherol oxidation, can function as an antioxidant after reduction to alpha… (More)
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Highly Cited
1995
Highly Cited
1995
Partial sequences of the 16S rRNA genes of the type strains of nine species of the genus Nocardia were determined following the… (More)
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Highly Cited
1992
Highly Cited
1992
NAD(P)H:quinone oxidoreductase (DT-diaphorase; DTD) is an obligate two-electron reductase which may play a role in the… (More)
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Highly Cited
1981
Highly Cited
1981
  • Microbiological reviews
  • 1981
[This corrects the article on p. 318 in vol. 45.]. 
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