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Somatic mutation
Known as:
Somatic Mutation Abnormality
, somatic mutations
Any mutation with an origin in cells that are not destined to become gametes. As a consequence, such mutations are not transmitted to progeny, though…
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National Institutes of Health
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Related topics
Related topics
31 relations
5q-syndrome
ACTH-INDEPENDENT MACRONODULAR ADRENAL HYPERPLASIA 2
BCL2 gene
Chronic Lymphocytic Leukemia
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Hereditary myeloproliferative disorders
R. Skoda
Haematologica
2010
Corpus ID: 11235329
Hereditary forms of myeloproliferative disorders (MPD) can be divided into two broad categories. First, inherited syndromes that…
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2004
2004
VH gene usage in immunoglobulin E responses of seasonal rhinitis patients allergic to grass pollen is oligoclonal and antigen driven
Janet M. Davies
,
Janet M. Davies
,
R. E. O'Hehir
,
R. E. O'Hehir
Clinical and Experimental Allergy
2004
Corpus ID: 11285590
Background IgE is the pivotal‐specific effector molecule of allergic reactions yet it remains unclear whether the elevated…
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1995
1995
Absence of somatic mutations in the coding region of the waf1/cip1 gene in human breast, lung and ovarian carcinomas - a polymorphism at codon-31.
A. Marchetti
,
F. Buttitta
,
S. Pellegrini
,
G. Bertacca
,
A. Lori
,
G. Bevilacqua
International Journal of Oncology
1995
Corpus ID: 46072667
Seventy-four invasive ductal, breast carcinomas, 73 non-small cell lung carcinomas and 36 ovarian adenocarcinomas, obtained from…
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1992
1992
B-cell proliferation initiated by Ia cross-linking and sustained by interleukins leads to class switching but not somatic mutation in vitro.
L. Wysocki
,
G. Creadon
,
K. Lehmann
,
J. Cambier
Immunology
1992
Corpus ID: 34738539
Somatic mutations that are acquired by antibody V genes of antigen-stimulated B cells ultimately provide the clonal diversity…
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1981
1981
How important are somatic mutations and immune control in skin cancer? Reflections on xeroderma pigmentosum.
B. Bridges
Carcinogenesis
1981
Corpus ID: 34786545
One of the key pieces of evidence in favour of the somatic mutation theory of cancer comes from the hereditary disease xeroderma…
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Review
1980
Review
1980
Drug-resistant lymphocytes in man as indicators of somatic cell mutation.
R. Albertini
Teratogenesis, carcinogenesis, and mutagenesis…
1980
Corpus ID: 21457319
Direct in vivo tests of somatic mutation in man may provide realism in assessing the genetic risks of potential environmental…
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Highly Cited
1977
Highly Cited
1977
Frequency of occurrence of idiotypes associated with anti-p- azophenylarsonate antibodies arising in mice immunologically suppressed with respect to a cross-reactive idiotype
S. Ju
,
A. Gray
,
A. Nisonoff
Journal of Experimental Medicine
1977
Corpus ID: 14133206
Inoculation of rabbit anti-idiotypic (anti-id) antibodies suppresses the subsequent appearance of a cross-reactive idiotype (CRI…
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1975
1975
Influence of radiation dose rate on somatic mutation induction in Tradescantia stamen hairs.
C. H. Nauman
,
A. G. Underbrink
,
A. Sparrow
Radiation Research
1975
Corpus ID: 28074907
Both X and gamma rays have been used to investigate the effect of dose rate on the induction of pink mutant cells in stamen hairs…
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Highly Cited
1975
Highly Cited
1975
Half chromatid mutations: transmission in humans?
S. Gartler
,
U. Francke
American Journal of Human Genetics
1975
Corpus ID: 33832498
Attention is drawn to the possibility of half chromatid and early somatic mutations and to several implications of these mosaic…
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1975
1975
Macronuclear genetics of Tetrahymena. II. Macronuclear location of somatic mutations to cycloheximide resistance.
E. Orias
,
C. Newby
Genetics
1975
Corpus ID: 41997309
Somatic cycloheximide-resistant mutants of syngen 1 of Tetrahymena pyriformis were isolated and genetically characterized. Two…
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