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Somatic mutation

Known as: Somatic Mutation Abnormality, somatic mutations 
Any mutation with an origin in cells that are not destined to become gametes. As a consequence, such mutations are not transmitted to progeny, though… 
National Institutes of Health

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Related topics

31 relations
5q-syndromeACTH-INDEPENDENT MACRONODULAR ADRENAL HYPERPLASIA 2BCL2 geneChronic Lymphocytic Leukemia

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2000
Review
2000
The structure and origin of rheumatoid factors.
Highly Cited
2000
Highly Cited
2000
Cultivated H-RS cells are resistant to CD95L-mediated apoptosis despite expression of wild-type CD95.
Highly Cited
1998
Highly Cited
1998
Interferon gamma-producing gammadelta T cell-dependent antibody isotype switching in the absence of germinal center formation during virus infection.
Ig class switching usually occurs as a consequence of cognate interactions between antigen-specific B cells and CD4(+) alphabeta… 
Highly Cited
1994
Highly Cited
1994
Evidence that the clonogenic cell in multiple myeloma originates from a pre‐switched but somatically mutated B cell
Summary. There is still much controversy about the precursor cell type in multiple myeloma (MM). Some authors claim that it is a… 
Review
1987
Review
1987
The genetic origin of autoantibodies.
Review
1984
Review
1984
The structural and genetic basis for expression of normal and latent VHa allotypes of the rabbit.
Highly Cited
1980
Highly Cited
1980
Expression of a variant form of actin and additional polypeptide changes following chemical-induced in vitro neoplastic transformation of human fibroblasts.
Highly Cited
1976
Highly Cited
1976
Somatic mutation as the basis for malignant transformation of BHK cells by chemical carcinogens
The chemical induction of malignant transformation in BHK cells seems to result from a somatic mutation. Stable transformants… 
Highly Cited
1975
Highly Cited
1975
Somatic genetic analysis of cyclic AMP action: Selection of unresponsive mutants
Dibutyryl cyclic AMP and theophylline kill S49.1 mouse lymphoma tissue culture cells. When cells are grown in soft agar with… 
Highly Cited
1969
Highly Cited
1969
Genetics of somatic mammalian cells. IX. Quantitation of mutagenesis by physical and chemical agents
The system previously described for inducing single gene mutations in Chinese hamster cells has been extended to produce… 
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