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Somatic mutation
Known as:
Somatic Mutation Abnormality
, somatic mutations
Any mutation with an origin in cells that are not destined to become gametes. As a consequence, such mutations are not transmitted to progeny, though…
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National Institutes of Health
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Related topics
Related topics
31 relations
5q-syndrome
ACTH-INDEPENDENT MACRONODULAR ADRENAL HYPERPLASIA 2
BCL2 gene
Chronic Lymphocytic Leukemia
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2001
Highly Cited
2001
Genotoxicity of dill (Anethum graveolens L.), peppermint (Menthaxpiperita L.) and pine (Pinus sylvestris L.) essential oils in human lymphocytes and Drosophila melanogaster.
J. Lazutka
,
J. Mierauskien
,
G. Slapšyt
,
V. Dedonyt
Food and Chemical Toxicology
2001
Corpus ID: 1573255
Highly Cited
1999
Highly Cited
1999
Coats' disease of the retina (unilateral retinal telangiectasis) caused by somatic mutation in the NDP gene: a role for norrin in retinal angiogenesis.
G. Black
,
G. Black
,
+6 authors
D. McLeod
Human Molecular Genetics
1999
Corpus ID: 17413603
Coats' disease is characterized by abnormal retinal vascular development (so-called 'retinal telangiectasis') which results in…
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Highly Cited
1998
Highly Cited
1998
Fas ligand—a double-edged sword
Youhai H. Chen
,
James M. Wilson
Nature Biotechnology
1998
Corpus ID: 29857059
Highly Cited
1997
Highly Cited
1997
Diffuse large cell lymphomas are derived from mature B cells carrying V region genes with a high load of somatic mutation and evidence of selection for antibody expression
R. Küppers
,
K. Rajewsky
,
M. Hansmann
European Journal of Immunology
1997
Corpus ID: 21470803
In the Revised European American Lymphoma (REAL) classification, several subtypes of high‐grade lymphomas were combined in the…
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Review
1994
Review
1994
Formation of the chicken B-cell repertoire: ontogenesis, regulation of Ig gene rearrangement, and diversification by gene conversion.
C. Reynaud
,
B. Bertocci
,
A. Dahan
,
J. Weill
Advances in Immunology
1994
Corpus ID: 32384803
Highly Cited
1985
Highly Cited
1985
The T-cell-independent immune response to the hapten NP uses a large repertoire of heavy chain genes
N. Maizels
,
A. Bothwell
Cell
1985
Corpus ID: 24347493
Highly Cited
1985
Highly Cited
1985
Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin
S. Clarke
,
K. Huppi
,
D. Ruezinsky
,
L. Staudt
,
W. Gerhard
,
M. Weigert
Journal of Experimental Medicine
1985
Corpus ID: 14225661
This study focuses on 10 BALB/c anti-influenza virus (A/PR/8/34) hemagglutinin antibodies that have light chains encoded by the…
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Highly Cited
1979
Highly Cited
1979
A κ-immunoglobulin gene is formed by site-specific recombination without further somatic mutation
Jonathan G. Seidman
,
E. E. Max
,
P. Leder
Nature
1979
Corpus ID: 4365585
The active gene for a κ light chain is formed by a somatic recombination event that joins one of several hundred variable region…
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Review
1974
Review
1974
Editorial: Do human tumors show a chromosome pattern specific for each etiologic agent?
Janet D. Rowley
Journal of the National Cancer Institute
1974
Corpus ID: 30253040
A hypothesis is presented proposing a specific relationship between chromosomes and etiologic agents of various tumors. The…
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Highly Cited
1969
Highly Cited
1969
Genetics of somatic mammalian cells. IX. Quantitation of mutagenesis by physical and chemical agents
F. Kao
,
T. Puck
Journal of Cellular Physiology
1969
Corpus ID: 32048060
The system previously described for inducing single gene mutations in Chinese hamster cells has been extended to produce…
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