FAQ

Small Inducible Cytokine B11

Known as: I-TAC protein, human, H174, Chemokine (C-X-C Motif) Ligand 11 
C-X-C motif chemokine 11 (94 aa, ~10 kDa) is encoded by the human CXCL11 gene. This protein plays a role in chemoattraction for interleukin-activated… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2018
05101519982018

Related topics

Related topics

17 relations
Biologic DevelopmentCXCL11 geneCXCL11 wt AlleleCentral Nervous System
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Broader (1)

Chemokine CXCL11

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Small Inducible Cytokine B11
Immune response
Epithelial Cells
Central Nervous System
Chemotaxis
Immunoregulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
A Th1/Th2-associated chemokine imbalance during infancy in children developing eczema, wheeze and sensitization.
BACKGROUND Analyses of circulating chemokines offer novel tools to investigate the T helper (Th)1/Th2 imbalance in allergic… (More)
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Highly Cited
2010
Highly Cited
2010
CXCR7 Functions as a Scavenger for CXCL12 and CXCL11
BACKGROUND CXCR7 (RDC1), the recently discovered second receptor for CXCL12, is phylogenetically closely related to chemokine… (More)
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Highly Cited
2009
Highly Cited
2009
Elucidation of CXCR7-mediated signaling events and inhibition of CXCR4-mediated tumor cell transendothelial migration by CXCR7 ligands.
CXCR7 binds chemokines CXCL11 (I-TAC) and CXCL12 (SDF-1) but does not act as a classical chemoattractant receptor. Using CCX771… (More)
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2009
2009
Imaging ligand-dependent activation of CXCR7.
Chemokine CXCL12 is proposed to promote multiple steps in growth of primary tumors and progression to metastatic disease in more… (More)
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Highly Cited
2005
Highly Cited
2005
CXCL11 attenuates bleomycin-induced pulmonary fibrosis via inhibition of vascular remodeling.
Aberrant vascular remodeling is a central hallmark for the development and progression of idiopathic pulmonary fibrosis. The… (More)
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2005
2005
The CXCR3 targeting chemokine CXCL11 has potent antitumor activity in vivo involving attraction of CD8+ T lymphocytes but not inhibition of angiogenesis.
The IFN-gamma-inducible and CXCR3-targeting human CXC chemokines CXCL9 (Mig) and CXCL10 (IP10) have potent antitumor activity… (More)
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Highly Cited
2004
Highly Cited
2004
Intracellular domains of CXCR3 that mediate CXCL9, CXCL10, and CXCL11 function.
The chemokine receptor CXCR3 is a G protein-coupled receptor found predominantly on T cells that is activated by three ligands as… (More)
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2004
2004
IFN-inducible protein 10/CXC chemokine ligand 10-independent induction of experimental autoimmune encephalomyelitis.
In multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), autoaggressive T cells traffic… (More)
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Highly Cited
2001
Highly Cited
2001
CXCR3 internalization following T cell-endothelial cell contact: preferential role of IFN-inducible T cell alpha chemoattractant (CXCL11).
Chemokine receptors are rapidly desensitized and internalized following ligand binding, a process that attenuates receptor… (More)
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1999
1999
Human IP-9: A keratinocyte-derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3).
Chemokines and their receptors play a crucial part in the recruitment of leukocytes into inflammatory sites. The CXC chemokines… (More)
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