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Simian virus 40

Known as: SV 40 Viruses, rhesus polyomavirus, Polyomavirus maccacae 1 
A small (40 to 45 nm) DNA virus of the genus Polyomavirus, family Papovaviridae; the cause of seemingly inapparent infections in monkeys, especially… Expand
National Institutes of Health

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Highly Cited
2002
Highly Cited
2002
While it is clear that cancer arises from the accumulation of genetic mutations that endow the malignant cell with the properties… Expand
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Highly Cited
2001
Highly Cited
2001
Simian virus 40 (SV40) is unusual among animal viruses in that it enters cells through caveolae, and the internalized virus… Expand
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Highly Cited
1996
Highly Cited
1996
Expression of vascular endothelial growth factor (VEGF) is induced in cells exposed to hypoxia or ischemia. Neovascularization… Expand
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Highly Cited
1991
Highly Cited
1991
The crystallographically determined structure of simian virus 40 shows that the 72 pentamers of viral protein VP1, which form the… Expand
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Highly Cited
1989
Highly Cited
1989
Deletions or mutations of the retinoblastoma gene, RB1, are common features of many tumors and tumor cell lines. Recently, the… Expand
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Highly Cited
1986
Highly Cited
1986
DNA coding for bacteriophage T7 RNA polymerase was ligated to a vaccinia virus transcriptional promoter and integrated within the… Expand
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Highly Cited
1985
Highly Cited
1985
Following the transfer into fertilized mouse eggs of recombinant genes composed of the upstream region of the rat insulin II gene… Expand
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Highly Cited
1984
Highly Cited
1984
A point mutation in the simian virus 40 large-T gene, which was generated by mixed oligonucleotide mutagenesis and resulted in… Expand
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Highly Cited
1977
Highly Cited
1977
Circular (e.g. simian virus 40) and linear (e.g. λ phage) DNAs have been labeled to high specific radioactivities (>108 cts/min… Expand
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Highly Cited
1972
Highly Cited
1972
We have developed methods for covalently joining duplex DNA molecules to one another and have used these techniques to construct… Expand
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