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EQUILIBRIUM SEDIMENTATION OF MACROMOLECULES IN DENSITY GRADIENTS.
This communication presents a new method for the study of the molecular weight and partial specific volume of macromolecules, with some illustrations based on results with deoxyribonucleic acid (DNA)Expand
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A dye-buoyant-density method for the detection and isolation of closed circular duplex DNA: the closed circular DNA in HeLa cells.
Covalently closed circular duplex DNA’s are now known to be widespread among living organisms. This DNA structure, originally identified in polyoma viral DNA,1’2 has been assigned to theExpand
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The twisted circular form of polyoma viral DNA.
The major part of the DNA from polyoma virus has been shown to consist of circular base-paired duplex molecules without chain ends.1–3 The intertwined circular form accounts for the ease ofExpand
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A novel closed-circular mitochondrial DNA with properties of a replicating intermediate.
A fraction of the covalently closed mitochondrial DNA in mouse L cells contains a replicated heavy-strand segment that is hydrogen bonded to the circular light strand. The inserted single strand isExpand
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THE DISTRIBUTION OF BUOYANT DENSITY OF HUMAN ERYTHROCYTES IN BOVINE ALBUMIN SOLUTIONS.
  • R. Leif, J. Vinograd
  • Chemistry, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1 March 1964
Several reports have appeared in the literature of the variation of "density" among different types of dispersed cells and of physical separations based upon this property. (1,2) Two generalExpand
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Replication of mitochondrial DNA. Circular replicative intermediates in mouse L cells.
The frequency, composition, and structure of circular replicating forms of mitochondrial DNA, including two new forms described here, suggest a scheme for the mode of replication of this DNA.
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THE CYCLIC HELIX AND CYCLIC COIL FORMS OF POLYOMA VIRAL DNA.
The DNA extracted from polyoma virus exhibits certain properties which have not been reported for other viral base-paired DNA’s.1 The DNA renatures monomolecularly. The loss of helical configurationExpand
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The evaluation of standard sedimentation coefficients of sodium RNA and sodium DNA from sedimentation velocity data in concentrated NaCl and CsCl solutions.
1. 1. The sedimentation velocity of the sodium and cesium salts of MS2 RNA and T7 DNA has been investigated in NaCl and CsCl solutions which range in concentrations from about 1 M to concentrationsExpand
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The bouyant behavior of viral and bacterial DNA in alkaline CsCl.
In equilibrium density gradient centrifugation, the banding polymer species is electrically neutral. The banding species for a negative polyelectrolyte with a polyanion P_(n)^(-z)n (where n is theExpand
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