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Pax7 Is Required for the Specification of Myogenic Satellite Cells
The paired box transcription factor Pax7 was isolated by representational difference analysis as a gene specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridizationExpand
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Pax-6, a murine paired box gene, is expressed in the developing CNS.
A multigene family of paired-box-containing genes (Pax genes) has been identified in the mouse. In this report, we describe the expression pattern of Pax-6 during embryogenesis and the isolation ofExpand
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Pax6 Is Required for the Multipotent State of Retinal Progenitor Cells
The molecular mechanisms mediating the retinogenic potential of multipotent retinal progenitor cells (RPCs) are poorly defined. Prior to initiating retinogenesis, RPCs express a limited set ofExpand
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Pax‐3, a novel murine DNA binding protein expressed during early neurogenesis.
We describe the isolation and characterization of Pax‐3, a novel murine paired box gene expressed exclusively during embryogenesis. Pax‐3 encodes a 479 amino acid protein with an Mr of 56 kdExpand
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Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development.
The Drosophila sine oculis homeobox-containing gene is known to play an essential role in controlling the initial events of pattern formation in the eye disc and is also required for the developmentExpand
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Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye.
The Pax6 transcription factor plays a key role in ocular development of vertebrates and invertebrates. Homozygosity of the Pax6 null mutation in human and mice results in arrest of optic vesicleExpand
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Pax6 Controls Radial Glia Differentiation in the Cerebral Cortex
Radial glia cells perform a dual function in the developing nervous system as precursor cells and guides for migrating neurons. We show here that during forebrain neurogenesis, the transcriptionExpand
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Roles of Pax-genes in developing and adult brain as suggested by expression patterns
  • A. Stoykova, P. Gruss
  • Biology, Medicine
  • The Journal of neuroscience : the official…
  • 1 March 1994
We have examined the transcript distribution of six members of the murine paired box-containing gene family (Pax-gene family) in midgestation embryo and adult brain using in situ hybridizationExpand
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Cre-mediated gene deletion in the mammary gland.
To delete genes specifically from mammary tissue using the Cre-lox system, we have established transgenic mice expressing Cre recombinase under control of the WAP gene promoter and the MMTV LTR. CreExpand
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Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system.
The murine genome contains multiple genes with protein domains homologous to the Drosophila paired box, present in certain segmentation genes. At least one of these murine paired box (Pax) genes isExpand
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