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Self Tolerance

Known as: Self Tolerances, Tolerance, Self, Tolerances, Self 
The normal lack of the ability to produce an immunological response to autologous (self) antigens. A breakdown of self tolerance leads to autoimmune… 
National Institutes of Health

Related topics

Related topics

6 relations
Autoimmune DiseasesClonal AnergyClonal DeletionImmune Tolerance

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Dermal nickel exposure associated with coin handling and in various occupational settings: assessment using a newly developed finger immersion method
Background  The role of nickel in causing hand dermatitis in some occupations has been difficult to assess due to problems with… 
Review
2001
Review
2001
Therapeutic aspects of tolerance.
Highly Cited
2000
Highly Cited
2000
TNF receptor 1 (TNFR1) and CD95 are not required for T cell deletion after virus infection but contribute to peptide‐induced deletion under limited conditions
Deletion of mature T cells maintains cellular homeostasis and is involved in the maintenance of self tolerance to some peripheral… 
1999
1999
A influência de valores pessoais de executivos brasileiros e argentinos em negociações comerciais
O aumento da competitividade global tem incentivado a integracao dos paises em blocos economicos. Em consequencia, o fluxo… 
Highly Cited
1996
Highly Cited
1996
Establishment of tissue‐specific tolerance is driven by regulatory T cells selected by thymic epithelium
Grafts of thymic epithelium (TE) rudiments restore T cell development and function in allogeneic athymic mice. These TE chimeras… 
Review
1993
Review
1993
The regulation of autoimmunity through CD4+ T cells.
Our experiments imply that it is possible to use monoclonal antibody therapy to reestablish self tolerance to self antigens. This… 
1992
1992
Self tolerance to human A and B histo‐blood group antigens exists at the B cell level and cannot be broken by potent polyclonal B cell activation in vitro
It is generally considered that tolerance to self antigens is less complete in B than in T lymphocytes. However, B cell tolerance… 
1987
1987
Specific helper T cell reactivity against autologous erythrocytes implies that self tolerance need not depend on clonal deletion
Using a culture system which supports primary T cell proliferative responses to various antigens we have detected mouse red blood… 
Review
1985
Review
1985
The Possible Role of Class II Major Histocompatibility Complex Antigens in Self Tolerance
The only known role of class II major histocompatibility complex (MHC) antigens is to serve as restriction elements in the… 
1984
1984
Swapping recipes for control.
The comments by Azuma and Kojima are both encouraging and thought provoking. We thoroughly agree that there may be multiple… 
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