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Sch 21420

Known as: Sch-21420 
National Institutes of Health

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1 relation

Broader (1)

isepamicin

Papers overview

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Highly Cited
1990
Highly Cited
1990
Appearance of amikacin and tobramycin resistance due to 4'-aminoglycoside nucleotidyltransferase [ANT(4')-II] in gram-negative pathogens
Following the use of amikacin as the principal aminoglycoside at a Denver hospital, amikacin resistance appeared first in… 
1980
1980
Interpretive standards for disk susceptibility tests with Sch 21420 and amikacin
Disk susceptibility tests with two structurally related aminoglycosides (amikacin and Sch 21420) were evaluated. Tests with 10… 
1980
1980
Comparison of in vitro activity of Sch 21420, a gentamicin B derivative, with those of amikacin, gentamicin, netilmicin, sisomicin, and tobramycin
Sch 21420 is a new aminoglycoside synthesized from gentamicin B. Susceptibility tests with Sch 21420, amikacin, gentamicin… 
1979
1979
Comparative nephrotoxicity of SCH 21420 and amikacin in rats
The nephrotoxic potentials of the new aminoglycoside SCH 21420 and amikacin were compared in a rat model. Groups of rats received… 
1978
1978
In Vitro Studies with Sch 21420 and Sch 22591: Activity in Comparison with Six Other Aminoglycosides and Synergy with Penicillin Against Enterococci
In vitro tests were performed with Sch 21420 and Sch 22591 to determine (i) their activity in comparison to six other… 
1978
1978
Biological activity of SCH 21420, the 1-N-S-alpha-hydroxy-beta-aminopropionyl derivative of gentamicin B.
Sch 21420, the 1-N-HAPA derivative of gentamicin B, has been compared to gentamicin, tobramycin and amikacin in a variety of in… 
1978
1978
In Vitro Activity of Sch 21420, Derivative of Gentamicin B, Compared to That of Amikacin
The minimal inhibitory concentration of Sch-21420 closely paralleled amikacin for 125 strains of aerobic gram-negative bacilli… 
1978
1978
In Vitro Evaluation of a Semisynthetic Derivative of Gentamicin B (SCH 21420)
The activities of Sch 21420 and amikacin were compared in vitro against 448 clinical bacterial isolates and against 82 gentamicin… 
1978
1978
Comparative in vitro activity of a semisynthetic derivative of gentamicin B (SCH 21420) and five other aminoglycosides.
With the increasing prevalence of Gramnegative bacilli resistant to existing aminoglycosides, new semisynthetic aminoglycosides… 
1978
1978
1-N-(S-3-amino-2-hydroxypropionyl) gentamicin B (Sch 21420): A collaborative in vitro susceptibility comparison with amikacin and gentamicin against 12,984 clinical bacterial isolates
Schering Compound Sch 21420 is an aminoglycoside with antibacterial activity similar to amikacin but with a potential for renal… 
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