STAT4 protein

Known as: Transcription Factor, STAT4, STAT4 Transcription Factor, STAT4 Transcription Factor [Chemical/Ingredient] 
A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-12 in T-LYMPHOCYTES. Stat4 is an important… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2018
020406019942018

Papers overview

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Highly Cited
2010
Highly Cited
2010
Signal transducer and activator of transcription 4 (STAT4) and STAT6 are key factors in the specification of helper T cells… (More)
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Highly Cited
2009
Highly Cited
2009
CD4(+) T cells producing interleukin-10 (IL-10) and interferon-gamma (IFN-gamma) are reported in chronic infections. However, the… (More)
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Highly Cited
2009
Highly Cited
2009
Increased IFN-alpha signaling is a primary pathogenic factor in systemic lupus erythematosus (SLE). STAT4 is a transcription… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Rheumatoid arthritis is a chronic inflammatory disease with a substantial genetic component. Susceptibility to disease… (More)
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Highly Cited
2007
Highly Cited
2007
A recent study in the North American White population has documented the association of a common STAT4 haplotype (tagged by… (More)
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Highly Cited
2003
Highly Cited
2003
Recent data support a modulatory role for CD4 T cells in experimental renal ischemia-reperfusion injury (IRI). CD4 T cells can… (More)
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Highly Cited
2002
Highly Cited
2002
Interferons (IFNs) are essential for host defense. Although the antiviral effects of the type 1 IFNs IFN-alpha and IFN-beta (IFN… (More)
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Highly Cited
2000
Highly Cited
2000
Interleukin (IL)-12 plays a critical role in modulating the activities of natural killer (NK) cells and T lymphocytes. In animal… (More)
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Highly Cited
1996
Highly Cited
1996
Interactions between cytokine and receptor lead to the activation of multiple signalling molecules, including the family of… (More)
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Highly Cited
1995
Highly Cited
1995
Interleukin 12 (IL-12) is an important immunoregulatory cytokine whose receptor is a member of the hematopoietin receptor… (More)
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