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STAT4 protein

Known as: Transcription Factor, STAT4, STAT4 Transcription Factor, STAT4 Transcription Factor [Chemical/Ingredient] 
A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-12 in T-LYMPHOCYTES. Stat4 is an important… 
National Institutes of Health

Papers overview

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2012
2012
Natural killer (NK) cells are involved in innate immune responses to viral infections either via direct cytotoxicity which… 
Highly Cited
2009
Highly Cited
2009
W Yang, P Ng, M Zhao, N Hirankarn, CS Lau, CC Mok, TM Chan, RWS Wong, KW Lee, MY Mok, SN Wong, Y Avihingsanon, TL Lee, MHK Ho… 
Highly Cited
2005
Highly Cited
2005
Psoriasis is a chronic inflammatory skin disease characterized by abnormal epidermal proliferation. Several studies have shown… 
Review
2005
Review
2005
Synthetic oligodeoxynucleotides (ODNs) expressing immunosuppressive TTAGGG motifs downregulate the production of proinflammatory… 
Highly Cited
2000
Highly Cited
2000
We used signal transducer and activator of transcription 4 (STAT4) and STAT6 gene knockout (-/-) mice as recipients of fully… 
Highly Cited
2000
Highly Cited
2000
Although Th1-type responses tend to be associated with resistance to Trypanosoma cruzi infection, mixed Th1 and Th2 cytokine… 
Highly Cited
1999
Highly Cited
1999
Recent studies have demonstrated that two IL‐12 signaling pathways, a STAT 4 – dependent and STAT4 – independent, are involved in… 
Highly Cited
1999
Highly Cited
1999
Interleukin-12(IL-12) promotes cell-mediated Th1 responses and production of IFN-gamma that downregulates IgE production. The… 
Highly Cited
1996
Highly Cited
1996
IL-12 is a powerful skewer of CD4+ T cell responses toward the Th1 phenotype by inducing IFN-gamma production in naive Th cells… 
Review
1996
Review
1996
The experiments described above have allowed us to define the molecular events in IL-12 signalling. Within minutes after IL-12…