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STAT4 protein

Known as: Transcription Factor, STAT4, STAT4 Transcription Factor, STAT4 Transcription Factor [Chemical/Ingredient] 
A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-12 in T-LYMPHOCYTES. Stat4 is an important… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
BACKGROUND Rheumatoid arthritis is a chronic inflammatory disease with a substantial genetic component. Susceptibility to disease… Expand
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Highly Cited
2007
Highly Cited
2007
IL-17-secreting CD4(+) T cells are critically involved in inflammatory immune responses. Development of these cells is promoted… Expand
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Highly Cited
2005
Highly Cited
2005
CD4+ T cells producing interleukin 17 (IL-17) are associated with autoimmunity, although the precise mechanisms that control… Expand
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Review
2004
Review
2004
Produced in response to a variety of pathogenic organisms, interleukin (IL)-12 and IL-23 are key immunoregulatory cytokines that… Expand
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Highly Cited
2002
Highly Cited
2002
Interferons (IFNs) are essential for host defense. Although the antiviral effects of the type 1 IFNs IFN-alpha and IFN-beta (IFN… Expand
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Highly Cited
2000
Highly Cited
2000
A novel sequence discovered in a computational screen appears distantly related to the p35 subunit of IL-12. This factor, which… Expand
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Review
2000
Review
2000
IL-4 and IL-12 are cytokines that are important regulators of the proliferation, differentiation and functional capacity of… Expand
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Highly Cited
1996
Highly Cited
1996
INTERACTIONS between cytokine and receptor lead to the activation of multiple signalling molecules, including the family of… Expand
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Highly Cited
1996
Highly Cited
1996
SIGNAL transducers and activators of transcription (STATs) are activated by tyrosine phosphorylation in response to cytokines and… Expand
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Highly Cited
1995
Highly Cited
1995
Interleukin 12 (IL-12) initiates the differentiation of naive CD4+ T cells to T helper type 1 (Th1) cells critical for resistance… Expand
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