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IL12 Signaling Pathway

Known as: IL12 and Stat4 Dependent Signaling Pathway in Th1 Development 
Interleukin-12 (IL-12) promotes cell-mediated immunity by inducing Th1 cell differentiation and activation of both T cells and NK cells. Dendritic… 
National Institutes of Health

Papers overview

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2018
2018
Background: Leishmaniasis is caused by parasitic protozoa of the genus Leishmania which is an obligate intracellular parasite in… 
2018
2018
Our earlier studies reported a unique potentiated combination (TriCurin) of curcumin (C) with two other polyphenols. The TriCurin… 
2018
2018
ABSTRACT Interleukin-12 (IL12) (p35/p40 complex) is a heterodimeric cytokine with potent anti-tumor activity. However, its short… 
2014
2014
  • D. Klinke
  • PLoS Comput. Biol.
  • 2014
  • Corpus ID: 449269
Innate and type 1 cell-mediated cytotoxic immunity function as important extracellular control mechanisms that maintain cellular… 
2014
2014
Long-term adherence to a high-fat, high-calorie diet influences human health and causes obesity, metabolic syndrome and… 
2012
2012
The IL-12p40/IL-12Rbeta1 and IFN-gammaR1/IFN-gammaR2/STAT1 signaling pathways are important for clearing intracellular bacteria… 
Review
2010
Review
2010
2007
2007
SummaryGlioblastoma multiforme (GBM) is an incurable brain tumor resistant to standard treatment modalities such as surgery… 
2005
2005
The production of IL-12 by macrophages/ dendritic cells (M4ilDC) is mediated either by a T celldependent pathway that is induced…