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IL12 Signaling Pathway

Known as: IL12 and Stat4 Dependent Signaling Pathway in Th1 Development 
Interleukin-12 (IL-12) promotes cell-mediated immunity by inducing Th1 cell differentiation and activation of both T cells and NK cells. Dendritic… Expand
National Institutes of Health

Papers overview

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2018
2018
Background: Leishmaniasis is caused by parasitic protozoa of the genus Leishmania which is an obligate intracellular parasite in… Expand
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2018
2018
Our earlier studies reported a unique potentiated combination (TriCurin) of curcumin (C) with two other polyphenols. The TriCurin… Expand
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2018
2018
ABSTRACT Interleukin-12 (IL12) (p35/p40 complex) is a heterodimeric cytokine with potent anti-tumor activity. However, its short… Expand
2014
2014
  • D. Klinke
  • PLoS Comput. Biol.
  • 2014
  • Corpus ID: 449269
Innate and type 1 cell-mediated cytotoxic immunity function as important extracellular control mechanisms that maintain cellular… Expand
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2014
2014
Long-term adherence to a high-fat, high-calorie diet influences human health and causes obesity, metabolic syndrome and… Expand
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2012
2012
The IL-12p40/IL-12Rbeta1 and IFN-gammaR1/IFN-gammaR2/STAT1 signaling pathways are important for clearing intracellular bacteria… Expand
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Review
2010
Review
2010
Despite recent progress, the pathogenic mechanisms governing PBC development, treatment response and outcome remain unknown. This… Expand
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2007
2007
SummaryGlioblastoma multiforme (GBM) is an incurable brain tumor resistant to standard treatment modalities such as surgery… Expand
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2006
2006
Peroxisome proliferator-activated receptor-gamma is a nuclear receptor transcription factor that regulates cell growth… Expand
2005
2005
The production of IL-12 by macrophages/ dendritic cells (M4ilDC) is mediated either by a T celldependent pathway that is induced… Expand
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