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Objective. The importance of hypomethylation in SLE is well recognized; however, the significance of hypermethylation has not… Expand Metastatic prostate cancer is the second leading cause of death from cancer in the United States. It is the first prevalent… Expand To decrease therapy-induced autoimmunity due to on-target toxicity against normal tissues, Lanitis and colleagues developed a… Expand Objective: Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease with complex genetic inheritance. CD247 (CD3Z… Expand Recently, a family-based association analysis showed that the haplotype carrying a low expression of the variant CD3Z 844 T>A… Expand cells. We aimed to test the hypothesis that the association between CD3Z genotype and TCRchain expression defined in patients… Expand CD8 T cells play an important role in protection and control of HIV-1 by direct cytolysis of infected cells and by suppression of… Expand Abstract The pyrolysis products of neutral methyl- d 3 t -butyl ether (MTBE- d 3 ), its undeuterated analogue, and t -octyl… Expand ABSTRACT Although human immunodeficiency virus (HIV)-infected subjects without AIDS have a high frequency of HIV-specific CD8 T… Expand One of the important mechanisms of immunosuppression in the tumor-bearing status has been attributed to the down-modulation of… Expand