CTL-mediated Immune Response Pathway
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Purpose: The carcinoembryonic antigen glypican-3 (GPC3) is an ideal target of anticancer immunotherapy against hepatocellular… Expand A reverse genetics strategy was used to insert the OVA peptide (amino acid sequence SIINFEKL; OVA257–264) into the neuraminidase… Expand Wild-type ErbB-2 (E2) positive D2F2/E2 tumors are rejected by active vaccination with ErbB-2 DNA. However, anti-ErbB-2 Ab… Expand Peptide epitopes for tumor‐reactive cytotoxic T‐lymphocytes (CTL) have been identified on human cancers and are being used in… Expand We have analyzed the presentation of human histocompatability leukocyte antigen-A*0201–associated tumor peptide antigen MAGE-3271… Expand Summary: Studies carried out using either mice or humans have shown that cytotoxic T‐lymphocyte (CTL) responses to many different… Expand Cytotoxic T lymphocytes (CTL) appear to play an important role in the control of human cytomegalovirus (HCMV) in the normal virus… Expand Although the immunologic basis of protective immunity in human immunodeficiency virus type 1 (HIV-1) infection has not yet been… Expand AIDS dementia complex is a common neurologic disorder in later stages of HIV-1 infection. Because virus-specific CTL have been… Expand Clones of cytotoxic T lymphocytes (CTL) differ in their specific reactivity with diverse target cell antigens. To learn about the… Expand