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CTL-mediated Immune Response Pathway

Known as: CTL mediated immune response against target cells 
Cytotoxic T lymphocytes (CTLs), also known as killer T cells, provide a cell-mediated response to specific foreign antigens associated with cells… 
National Institutes of Health

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19 relations
CD247 wt AlleleCD3D protein, humanCD3D wt AlleleCD3E protein, human

Papers overview

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2006
2006
Epstein‐Barr virus (EBV) latent membrane protein‐1‐specific cytotoxic T lymphocytes targeting EBV‐carrying natural killer cell malignancies
Epstein‐Barr virus (EBV)‐encoded latent membrane protein (LMP) 1 is a potential target for immunotherapy of some proportion of… 
2004
2004
Cross‐presentation of a human tumor antigen delivered to dendritic cells by HSV VP22‐mediated protein translocation
Dendritic cells (DC) capture antigens from apoptotic and/or necrotic tumor cells and cross‐present them to T cells, and various… 
Highly Cited
2002
Highly Cited
2002
The Immunodominant, Ld-Restricted T Cell Response to Hepatitis B Surface Antigen (HBsAg) Efficiently Suppresses T Cell Priming to Multiple Dd-, Kd-, and Kb-Restricted HBsAg Epitopes1
MHC-I-restricted CTL responses of H-2d (Ld+ or Ld−) and F1 H-2dxb mice to hepatitis B surface Ag (HBsAg) are primed by either DNA… 
1993
1993
Abrogation of H-2-restricted CTL responses and efficient recognition of HLA-A3 molecules in DBA/2 HLA/A24 responder mice.
DBA/2 (H-2d) HLA-B7 x human beta 2-microglobulin transgenic and DBA/2 nontransgenic mice stimulated by DBA/2 HLA-A3 x human beta… 
1993
1993
Differential binding of a minor histocompatibility antigen peptide to H-2 class I molecules correlates with immune responsiveness.
Minor histocompatibility (H) Ag are recognized in the context of MHC class I (K/D) molecules and can constitute a strong barrier… 
1992
1992
Single-residue changes in class I major histocompatibility complex molecules stimulate responses to self peptides.
Single-residue changes were introduced into the murine major histocompatibility complex class I molecule H-2Kb at positions 65… 
1987
1987
Mutual tolerization of histoincompatible lymphocytes
T lymphocytes react strongly against foreign major histocompatibility complex encoded class I antigens by destroying incompatible… 
1986
1986
Involvement of the T cell antigen receptor and of Lyt-2 in the cytotoxic function of aged killer (AK) T cells
Aged killer (AK) T cells are antigen-independent, IL-2-requiring variants of antigen-dependent CTL clones that have lost their… 
1982
1982
Selection of the T cell repertoire during ontogeny: Limiting dilution analysis
The relative frequencies of cytotoxic T lymphocyte precursors (CTL‐P) specific for minor histocompatibility antigens that are… 
1982
1982
Cell-mediated lympholysis responses against autologous cells modified with haptenic sulfhydryl reagents. IV. Self-determinants recognized by wild-type anti-H-2Kb and H-2Db-restricted cytotoxic T…
Virus-specific H-2-restricted cytotoxic T cells (CTL) have been found to discriminate between wild-type and mutant class I… 
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