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CD247 gene

Known as: CD247 ANTIGEN, CD247 Molecule Gene, CD3Z 
This gene plays a role in immunity/defense.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
The CD3 ζ chain (CD247), a gene involved in T-cell signaling, has been shown to associate with blood pressure in human genetic… Expand
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Highly Cited
2010
Highly Cited
2010
Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of the skin and internal organs that leads to… Expand
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Highly Cited
2007
Highly Cited
2007
Preliminary results from a pilot trial on trastuzumab's mechanism of action against operable breast tumors overexpressing Her2… Expand
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Highly Cited
2006
Highly Cited
2006
Exosome release by viable cells is a feature of activated cell types, including tumors, fetal cells, and cells of the immune… Expand
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Highly Cited
2006
Highly Cited
2006
PROBLEM One immunoregulatory pathway receiving little attention is placental exosome release. In normal pregnancy, as factors… Expand
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Highly Cited
2003
Highly Cited
2003
PURPOSE The accumulation of shed plasma membrane vesicles in the peripheral circulation is unique to cancer. Because these… Expand
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2002
2002
BACKGROUND Impaired or reduced CD3 zeta chain (CD3-zeta) expression in T cells has been identified in various cancers and may be… Expand
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1998
1998
In myeloid malignancies, T-cell and NK function has been shown to deteriorate with transformation from pre-leukaemia to advanced… Expand
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Highly Cited
1997
Highly Cited
1997
T cell activation by specific antigen results in a rapid and long-lasting downregulation of triggered T cell receptors (TCRs). In… Expand
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Highly Cited
1992
Highly Cited
1992
Recent studies have demonstrated that the CD3-zeta subunit of the T cell antigen receptor (TCR) complex is involved in signal… Expand
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