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SR 48968

Known as: SR48968C, SR-48968C, SR48968 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

BenzamidesPiperidines

Narrower (1)

saredutant

Papers overview

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2006
2006
Pharmacological correlation between the formalin test and the neuropathic pain behavior in different species with chronic constriction injury
Highly Cited
2004
Highly Cited
2004
Evidence for the presence of functional protease activated receptor 4 (PAR4) in the rat colon
Background and aims: Protease activated receptors (PARs) have been postulated to play a role during intestinal inflammation. The… 
2003
2003
Involvement of nitric oxide and tachykinins in the effects induced by protease‐activated receptors in rat colon longitudinal muscle
The aim of the present study was to verify a possible involvement of nitric oxide (NO) and of tachykinins in the contractile and… 
2002
2002
Facilitation by Endogenous Tachykinins of the NMDA-Evoked Release of Acetylcholine after Acute and Chronic Suppression of Dopaminergic Transmission in the Matrix of the Rat Striatum
Using a microsuperfusion method in vitro, the effects of the NK1, NK2, and NK3 tachykinin receptor antagonists SR140333, SR48968… 
2002
2002
Interactions of Volatile Anesthetics with Cholinergic, Tachykinin, and Leukotriene Mechanisms in Isolated Guinea Pig Bronchial Smooth Muscle
We studied relaxation of airway smooth muscle by sevoflurane, desflurane, and halothane in isolated guinea pig bronchi. Ring… 
1999
1999
Nanomolar concentrations of neuropeptides induce histamine release from peritoneal mast cells of a substrain of Wistar rats.
1999
1999
Role of tachykinin NK2‐receptor activation in the allergen‐induced late asthmatic reaction, airway hyperreactivity and airway inflammatory cell influx in conscious, unrestrained guinea‐pigs
In a guinea‐pig model of allergic asthma, we investigated the involvement of the tachykinin NK2 receptors in allergen‐induced… 
Highly Cited
1998
Highly Cited
1998
Activation of spinal N-methyl-d-aspartate or neurokinin receptors induces long-term potentiation of spinal C-fibre-evoked potentials in spinalized rats
Highly Cited
1996
Highly Cited
1996
Induction of hyperresponsiveness in human airway tiss by neutrophils — mechanism of action
Background The two main features of asthtna are bronchial hyperresponsiveness and inflammation. The inflammatory response in… 
Highly Cited
1995
Highly Cited
1995
Effect of the two tachykinin antagonists, SR 48968 and SR 140333, on cough induced by citric acid in the unanaesthetized guinea pig.
It is now well-established that sensory nerves stimulation in the airway induces bronchoconstriction and inflammation, but also… 
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