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saredutant

 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
These experiments were undertaken to assess the mechanisms underlying the antidepressant-like effects of the neurokinin-2 (NK(2… Expand
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2010
2010
Previous work established that saredutant, an NK2 receptor antagonist, has antidepressant and anxiolytic-antistress effects in a… Expand
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Highly Cited
2008
Highly Cited
2008
Central tachykinins have been shown to play a role in the modulation of stress-related behaviours. Saredutant, a tachykinin NK2… Expand
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2008
2008
The present study was made to investigate the role of tachykinin NK2 receptors in the expression of stress-related behaviors in… Expand
Highly Cited
2006
Highly Cited
2006
There is a growing interest in the potential anxiolytic- and antidepressant-like effects of compounds that target neurokinin… Expand
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2000
2000
The purpose of this work was to investigate the role of tachykinins in cough induced by citric acid (0.8 M) in pigs. With this… Expand
Highly Cited
1998
Highly Cited
1998
Inhalation of neurokinin (NK) A causes bronchoconstriction in patients with asthma. The NKA-induced bronchoconstriction in… Expand
Highly Cited
1998
Highly Cited
1998
Aerosolized citric acid induces several pulmonary effects including bronchoconstriction, airway inflammation, and cough. Evidence… Expand
1998
1998
Tachykinins, such as substance P, might be involved in the development of airway hyperresponsiveness and airway inflammation. 
1997
1997
Aerosolized substance P (0.1 M, for 30 min) induced airway hyperresponsiveness in guinea-pigs 24 h after they were pre-treated… Expand